Amin H. Sabet

The KDM5A/RBP2 histone demethylase represses NOTCH signaling to sustain neuroendocrine differentiation and promote small cell lung cancer tumorigenesis

Matthew G. Oser, Amin H. Sabet, Wenhua Gao et al. · Genes & Development · 2019 · 118 citations · Full text

Targeting oncoproteins with a positive selection assay for protein degraders

Vidyasagar Koduri, Leslie Duplaquet, Benjamin L. Lampson et al. · Science Advances · 2021 · 44 citations · Full text

Protein Degraders, Drug Target, Molecular Regulation +19

Exportin 1 inhibition prevents neuroendocrine transformation through SOX2 down-regulation in lung and prostate cancers

Àlvaro Quintanal-Villalonga, Vidushi Durani, Amin H. Sabet et al. · Science Translational Medicine · 2023 · 40 citations · Full text

Sox2 Down-regulation, Prostate Cancers, Exportin 1 +14

Plasticity in the Absence of NOTCH Uncovers a RUNX2-Dependent Pathway in Small Cell Lung Cancer

Deli Hong, Erik H. Knelson, Yixiang Li et al. · Cancer Research · 2021 · 36 citations · Full text

Regulation of neuroendocrine plasticity by the RNA-binding protein ZFP36L1

Hsiao-Yun Chen, Yavuz T. Durmaz, Yixiang Li et al. · Nature Communications · 2022 · 36 citations · Full text

Molecular Regulation, Genetics, Epigenetics +16