Yoshitaka Ogita

Transforming mutations of RAC guanosine triphosphatases in human cancers

Masahito Kawazu, Toshihide Ueno, Kenji Kontani et al. · Proceedings of the National Academy of Sciences · 2013 · 125 citations · Full text

Medicine, Cancer Biology, Molecular Biology +17

EOS789, a broad-spectrum inhibitor of phosphate transport, is safe with an indication of efficacy in a phase 1b randomized crossover trial in hemodialysis patients

Kathleen M. Hill Gallant, Elizabeth R. Stremke, Laurie L. Trevino et al. · Kidney International · 2020 · 42 citations · Full text

Medicine, Nephrology, Pharmacology +17

Phase I and pharmacokinetic/pharmacodynamic study of RO5126766, a first-in-class dual Raf/MEK inhibitor, in Japanese patients with advanced solid tumors

Kazunori Honda, Noboru Yamamoto, Hiroshi Nokihara et al. · Cancer Chemotherapy and Pharmacology · 2013 · 29 citations

Medicine, Pharmacokinetics, Pharmacology +15

Di-Ras2 Protein Forms a Complex with SmgGDS Protein in Brain Cytosol in Order to Be in a Low Affinity State for Guanine Nucleotides

Yoshitaka Ogita, Sachiko Egami, Arisa Ebihara et al. · Journal of Biological Chemistry · 2015 · 18 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

Phase I and pharmacokinetics/pharmacodynamics study of the MEK inhibitor RO4987655 in Japanese patients with advanced solid tumors

Shinji Nakamichi, Hiroshi Nokihara, Noboru Yamamoto et al. · Investigational New Drugs · 2015 · 15 citations

Medicine, Pharmacokinetics, Pharmacology +12