John Higgins

Carboxylation of Kinetically Inert Platinum(IV) Hydroxy Complexes. An Entr.acte.ee into Orally Active Platinum(IV) Antitumor Agents

Christen M. Giandomenico, Michael J. Abrams, Barry A. Murrer et al. · Inorganic Chemistry · 1995 · 247 citations

Pharmaceutical Science, Altmetric Attention Score, Hydroxy Complexes +16

A Series of Novel, Highly Potent, and Orally Bioavailable Next-Generation Tricyclic Peptide PCSK9 Inhibitors

Thomas J. Tucker, Mark W. Embrey, Candice Alleyne et al. · Journal of Medicinal Chemistry · 2021 · 140 citations · Full text

Impact of Surfactants on the Crystallization of Aqueous Suspensions of Celecoxib Amorphous Solid Dispersion Spray Dried Particles

Jie Chen, James D. Ormes, John Higgins et al. · Molecular Pharmaceutics · 2015 · 131 citations

Materials Science, Food Chemistry, Chemical Engineering +14

Bile Salts as Crystallization Inhibitors of Supersaturated Solutions of Poorly Water-Soluble Compounds

Jie Chen, Laura I. Mosquera-Giraldo, James D. Ormes et al. · Crystal Growth & Design · 2015 · 84 citations

Pharmaceutical Science, Supersaturation Behavior, Organic Chemistry +19

Strategies at the Interface of Drug Discovery and Development: Early Optimization of the Solid State Phase and Preclinical Toxicology Formulation for Potential Drug Candidates

Michael Palucki, John Higgins, Elizabeth Kwong et al. · Journal of Medicinal Chemistry · 2010 · 66 citations

Pharmaceutical Science, Drug Target, Solid State Phase +17