Ian S. Galloway

Divergent sequence motifs correlated with the substrate specificity of (methyl)malonyl‐CoA:acyl carrier protein transacylase domains in modular polyketide synthases

Stephen Haydock, Jesús F. Aparicio, István Molnár et al. · FEBS Letters · 1995 · 241 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Knowledge-based design of bimodular and trimodular polyketide synthases based on domain and module swaps: a route to simple statin analogues

Anand Ranganathan, M C Timoney, Jesús Cortés et al. · Chemistry & Biology · 1999 · 102 citations · Full text

Pharmacy, Biotechnology, Medicinal Chemistry +17

A Polylinker Approach to Reductive Loop Swaps in Modular Polyketide Synthases

Laurenz Kellenberger, Ian S. Galloway, Guido Sauter et al. · ChemBioChem · 2008 · 65 citations

Life Sciences, Biotechnology, Molecular Biology +15

Direct production of ivermectin-like drugs after domain exchange in the avermectin polyketide synthase of Streptomyces avermitilis ATCC31272

Sabine Gaisser, Laurenz Kellenberger, Andrew L. Kaja et al. · Organic & Biomolecular Chemistry · 2003 · 46 citations

Pharmacy, Infectious Diseases, Microbiology +16