Edel Hennessy

A Systematic Analysis of the Peripheral and CNS Effects of Systemic LPS, IL-1Β, TNF-α and IL-6 Challenges in C57BL/6 Mice

Donal Skelly, Edel Hennessy, Marc‐André Dansereau et al. · PLoS ONE · 2013 · 269 citations · Full text

Systemic Lps, Immunology, Immune Regulation +27

Acute systemic inflammation exacerbates neuroinflammation in Alzheimer's disease: IL‐1β drives amplified responses in primed astrocytes and neuronal network dysfunction

Ana Belén López-Rodríguez, Edel Hennessy, Carol Murray et al. · Alzheimer s & Dementia · 2021 · 250 citations · Full text

Acute Systemic Inflammation, Immunology, Neuroinflammation +16

Co-morbidity and systemic inflammation as drivers of cognitive decline: new experimental models adopting a broader paradigm in dementia research

Colm Cunningham, Edel Hennessy · Alzheimer s Research & Therapy · 2015 · 207 citations · Full text

Astrocytes Are Primed by Chronic Neurodegeneration to Produce Exaggerated Chemokine and Cell Infiltration Responses to Acute Stimulation with the Cytokines IL-1β and TNF-α

Edel Hennessy, Éadaoin W. Griffin, Colm Cunningham · Journal of Neuroscience · 2015 · 168 citations · Full text

Immunology, Immune Regulation, Cell Death +17

Worsening Cognitive Impairment and Neurodegenerative Pathology Progressively Increase Risk for Delirium

Daniel Davis, Donal Skelly, Carol Murray et al. · American Journal of Geriatric Psychiatry · 2014 · 133 citations · Full text