R. van de Straat

Abstract of papers

Antonius W.T. Konings, H. Joenje, Aalt Bast et al. · Pharmacy World & Science · 1987 · 428 citations

Document Engineering, Abstract Object Theory, Abstract Analysis

The mechanism of prevention of paracetamol-induced hepatotoxicity by 3,5-dialkyl substitution

R. van de Straat, J. de Vries, A.J.J. Debets et al. · Biochemical Pharmacology · 1987 · 78 citations

Allergy, Hepatology, Medicine +8

Cytochrome P-450-mediated oxidation of substrates by electron-transfer; Role of oxygen radicals and of 1- and 2-electron oxidation of paracetamol

R. van de Straat, R. M. Vromans, Patrick Bosman et al. · Chemico-Biological Interactions · 1988 · 40 citations

2-Electron Oxidation, Biochemistry, Medicine +10

A theoretical study on the metabolic activation of paracetamol by cytochrome P-450: indications for a uniform oxidation mechanism

Luc Koymans, Joop H. van Lenthe, R. van de Straat et al. · Chemical Research in Toxicology · 1989 · 40 citations

Phenolic Oxygen, Metabolic Activation, Organic Chemistry +16

Paracetamol, 3-monoalkyl- and 3,5-dialkyl derivatives

R. van de Straat, J. de Vries, T. Kulkens et al. · Biochemical Pharmacology · 1986 · 39 citations

Derivative (Chemistry), Derivatives, 3,5-Dialkyl Derivatives +3