R. van de Straat

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Publications

Citations

767

H-Index

Active since

1986

Affiliations

University of Amsterdam(Current)

Vrije Universiteit Amsterdam

Society of Environmental Toxicology and Chemistry

R. van de Straat is an author at University of Amsterdam specializing in pharmacology, cytochrome p450-mediated metabolism, and cytochrome p450 enzymes.

Publications per year

1986–1990

Publications

Abstract of papers

Antonius W.T. Konings, H. Joenje, Aalt Bast et al. · Pharmacy World & Science · 1987 · 428 citations

The mechanism of prevention of paracetamol-induced hepatotoxicity by 3,5-dialkyl substitution

R. van de Straat, J. de Vries, A.J.J. Debets et al. · Biochemical Pharmacology · 1987 · 79 citations

Pharmacy, Pharmacology, Toxicology +11

Cytochrome P-450-mediated oxidation of substrates by electron-transfer; Role of oxygen radicals and of 1- and 2-electron oxidation of paracetamol

R. van de Straat, R. M. Vromans, Patrick Bosman et al. · Chemico-Biological Interactions · 1988 · 40 citations

Life Sciences, Biochemistry, Pharmacology +15

A theoretical study on the metabolic activation of paracetamol by cytochrome P-450: indications for a uniform oxidation mechanism

Luc Koymans, Joop H. van Lenthe, R. van de Straat et al. · Chemical Research in Toxicology · 1989 · 40 citations

Medicine, Biochemistry, Pharmacology +17

Paracetamol, 3-monoalkyl- and 3,5-dialkyl derivatives

R. van de Straat, J. de Vries, T. Kulkens et al. · Biochemical Pharmacology · 1986 · 39 citations

Medicine, Medicinal Chemistry, Pharmacology +2

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