The tumor suppressor folliculin regulates AMPK-dependent metabolic transformation

Ming Yan, Marie Claude Gingras, Elaine A. Dunlop, +18

Journal of Clinical Investigation

Flcn-negative Cancer CellsMetabolic RemodelingWarburg EffectCancer BiologyTumor Biology +16

Folliculin Regulates Ampk-Dependent Autophagy and Metabolic Stress Survival

Elite Possik, Zahra Jalali, Yann Nouët, +10

PLoS Genetics

MitophagyAmpk SignalingCell DeathTumor BiologyCell Autophagy +16

The Transcription Factors TFEB and TFE3 Link the FLCN-AMPK Signaling Axis to Innate Immune Response and Pathogen Resistance

Leeanna El–Houjeiri, Elite Possik, Tarika Vijayaraghavan, +8

Cell Reports

Phosphatidylinositol-5-Phosphate 4-Kinases Regulate Cellular Lipid Metabolism By Facilitating Autophagy

Mark R. Lundquist, Marcus D. Goncalves, Ryan M. Loughran, +20

Molecular Cell

Cell AutophagyMitophagySignal TransductionAutophagyLipophagy +4

FLCN and AMPK Confer Resistance to Hyperosmotic Stress via Remodeling of Glycogen Stores

Elite Possik, Andrew Ajisebutu, Sanaz Manteghi, +9

PLoS Genetics

Biophysical ModelingMolecular RegulationGlycogen StoresGlycobiologyMolecular Biology +20

Measuring Oxidative Stress Resistance of <em>Caenorhabditis elegans</em> in 96-well Microtiter Plates

Elite Possik, Arnim Pause

Journal of Visualized Experiments

Lipid PeroxidationMolecular BiologyCaenorhabditis ElegansRedox BiologyOxidative Stress +14

Phosphoglycolate phosphatase homologs act as glycerol-3-phosphate phosphatase to control stress and healthspan in C. elegans

Elite Possik, Clémence Schmitt, Anfal Al‐Mass, +9

Nature Communications

Glycerol 3-phosphate phosphatase/PGPH-2 counters metabolic stress and promotes healthy aging via a glycogen sensing-AMPK-HLH-30-autophagy axis in C. elegans

Elite Possik, Laura-Lee Klein, Perla Sanjab, +12

Nature Communications

Hepatic glycerol shunt and glycerol-3-phosphate phosphatase control liver metabolism and glucodetoxification under hyperglycemia

Anfal Al‐Mass, Pegah Poursharifi, Marie‐Line Peyot, +12

Molecular Metabolism

Glycerol-3-phosphate phosphatase operates a glycerol shunt in pancreatic β-cells that controls insulin secretion and metabolic stress

Anfal Al‐Mass, Pegah Poursharifi, Marie‐Line Peyot, +10

Molecular Metabolism