An infectivity-enhancing site on the SARS-CoV-2 spike protein targeted by antibodies

Yafei Liu, Wai Tuck Soh, Jun-ichi Kishikawa, +34

Cell

Vaccine TargetViral PathogenesisImmunologyInfectivity-enhancing SiteVirology +5

Engineered ACE2 receptor therapy overcomes mutational escape of SARS-CoV-2

Yusuke Higuchi, Tatsuya Suzuki, Takao Arimori, +15

Nature Communications

SARS-CoV-2 infection triggers paracrine senescence and leads to a sustained senescence-associated inflammatory response

Shunya Tsuji, Shohei Minami, Rina Hashimoto, +21

Nature Aging

Effective Production of Levulinic Acid from Biomass through Pretreatment Using Phosphoric Acid, Hydrochloric Acid, or Ionic Liquid

Yosuke Muranaka, Tatsuya Suzuki, Hiroyuki Sawanishi, +2

Industrial & Engineering Chemistry Research

Biomass UtilizationIonic LiquidChemical EngineeringBiomass ConversionBiofuel Production +12

An engineered ACE2 decoy neutralizes the SARS-CoV-2 Omicron variant and confers protection against infection in vivo

Nariko Ikemura, Shunta Taminishi, Tohru Inaba, +15

Science Translational Medicine

Confers ProtectionEfficient EvasionImmunologyViral PathogenesisViral Structural Protein +14

SARS-CoV-2 ORF6 disrupts nucleocytoplasmic trafficking to advance viral replication

Yoichi Miyamoto, Yumi Itoh, Tatsuya Suzuki, +12

Communications Biology

Viral ReplicationViral PathogenesisImmunologyViral Structural ProteinTranscriptional Regulation +15

Discovery of 3-Ethyl-4-(3-isopropyl-4-(4-(1-methyl-1<i>H</i>-pyrazol-4-yl)-1<i>H</i>-imidazol-1-yl)-1<i>H</i>-pyrazolo[3,4-<i>b</i>]pyridin-1-yl)benzamide (TAS-116) as a Potent, Selective, and Orally Available HSP90 Inhibitor

Takao Uno, Yuichi Kawai, Satoshi Yamashita, +13

Journal of Medicinal Chemistry

TRC8-dependent degradation of hepatitis C virus immature core protein regulates viral propagation and pathogenesis

Sayaka Aizawa, Toru Okamoto, Yukari Sugiyama, +16

Nature Communications

Activation of the Complement System by (1.RAR.3)-.BETA.-D-Glucans Having Different Degrees of Branching and Different Ultrastructures.

Tatsuya Suzuki, Naohito Ohno, Kazuo Saito, +1

Journal of Pharmacobio-Dynamics

Sensitive Detection of Estrogenic Mycotoxin Zearalenone by Open Sandwich Immunoassay

Tatsuya Suzuki, Yuriko Munakata, Kazuki Morita, +2

Analytical Sciences

Estrogenic Mycotoxin ZearalenoneAllergyMycotoxin FormationBioanalysisMycotoxins +2