A Practical Guide to Rodent Islet Isolation and Assessment

Jeffrey D. Carter, Stacey B. Dula, Kathryn L. Corbin, +2

Biological Procedures Online

Unique motifs and hydrophobic interactions shape the binding of modified DNA ligands to protein targets

D.R. Davies, Amy D. Gelinas, Chi Zhang, +12

Proceedings of the National Academy of Sciences

Protein AssemblyPeptide EngineeringMolecular BiologyChemical BiologyProtein Folding +17

Modified aptamers enable quantitative sub-10-nm cellular DNA-PAINT imaging

Sebastian Strauss, Philipp C. Nickels, Maximilian T. Strauss, +6

Nature Methods

Dna NanotechnologyEngineeringMolecular BiologyMolecular ImagingCell Imaging +1

Selection of DNA aptamers with two modified bases

Bharat Gawande, John C. Rohloff, Jeffrey D. Carter, +4

Proceedings of the National Academy of Sciences

Rna AptamersEngineeringMolecular BiologyChemical BiologyNucleic Acid Biomarkers +15

Chemically Modified DNA Aptamers Bind Interleukin-6 with High Affinity and Inhibit Signaling by Blocking Its Interaction with Interleukin-6 Receptor

Shashi Kumar Gupta, Masao Hirota, Sheela Waugh, +12

Journal of Biological Chemistry

InflammationCytokineImmunologyMolecular BiologyImmunologic Mechanism +6

12-Lipoxygenase-knockout mice are resistant to inflammatory effects of obesity induced by western diet

Craig S. Nunemaker, Meng Chen, Hong Pei, +9

American Journal of Physiology-Endocrinology and Metabolism

Circulating Levels of IL-1B+IL-6 Cause ER Stress and Dysfunction in Islets From Prediabetic Male Mice

Christina M. O’Neill, Christine Y. Lu, Kathryn L. Corbin, +7

Endocrinology

InflammationMetabolic SyndromeCytokineAutoimmune DiseaseMedicine +13

Crystal Structure of Interleukin-6 in Complex with a Modified Nucleic Acid Ligand

Amy D. Gelinas, D.R. Davies, Thomas E. Edwards, +9

Journal of Biological Chemistry

CytokineMolecular ImmunologyCrystal StructureNucleic Acid ChemistryNatural Sciences +7

Nonobese Diabetic (NOD) Mice Congenic for a Targeted Deletion of 12/15-Lipoxygenase Are Protected From Autoimmune Diabetes

Marcia McDuffie, Nelly A. Maybee, Susanna R. Keller, +10

Diabetes

Valsartan Protects Pancreatic Islets and Adipose Tissue From the Inflammatory and Metabolic Consequences of a High-Fat Diet in Mice

Banumathi K. Cole, Susanna R. Keller, Runpei Wu, +3

Hypertension

ImmunologyHigh-fat DietGlucose ToleranceInsulin SignalingGastrointestinal Peptide Hormone +15