APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy

Anne Rovelet‐Lecrux, Didier Hannequin, Grégory Raux, +10

Nature Genetics

Alzheimer's DiseaseCerebral Amyloid AngiopathyDementiaNeurochemical BiomarkersNeurology +7

Cytoskeleton proteins are modulators of mutant tau-induced neurodegeneration in Drosophila

Olivier Blard, Sébastien Feuillette, Jacqueline Bou, +4

Human Molecular Genetics

Neurodegenerative DiseasesProtein FunctionDevelopmental BiologyMolecular NeuroscienceCytoskeleton Proteins +11

<i>Drosophila</i> models of human tauopathies indicate that Tau protein toxicity <i>in vivo</i> is mediated by soluble cytosolic phosphorylated forms of the protein

Sébastien Feuillette, Laëtitia Miguel, Thierry Frébourg, +2

Journal of Neurochemistry

Molecular BiologyCell DeathCytoskeletonToxicological MechanismAlzheimer's Disease +18

Accumulation of insoluble forms of FUS protein correlates with toxicity in Drosophila

Laëtitia Miguel, Tracey Avequin, Morgane Delarue, +4

Neurobiology of Aging

BiologyInsoluble FormsNatural SciencesFus ProteinMolecular Biology +4

Tau is not normally degraded by the proteasome

Sébastien Feuillette, Olivier Blard, Magalie Lecourtois, +3

Journal of Neuroscience Research

Important neuronal toxicity of microtubule-bound Tau in vivo in Drosophila

Yasmina Talmat-Amar, Yoan Arribat, Christelle Redt‐Clouet, +4

Human Molecular Genetics

Neurochemical BiomarkersCytoskeletonMicrotubule-associated Protein TauCellular NeurobiologyTau Protein +15

Impaired SorLA maturation and trafficking as a new mechanism for SORL1 missense variants in Alzheimer disease

Anne Rovelet‐Lecrux, Sébastien Feuillette, Laëtitia Miguel, +11

Acta Neuropathologica Communications

Filamin-A and Myosin VI colocalize with fibrillary Tau protein in Alzheimer's disease and FTDP-17 brains

Sébastien Feuillette, Vincent Deramecourt, A. Laquérrière, +8

Brain Research

Alzheimer's DiseaseMolecular NeuroscienceDementiaFtdp-17 BrainsDegenerative Disease +12

Lack of miRNA Misregulation at Early Pathological Stages in Drosophila Neurodegenerative Disease Models

Anita Reinhardt, Sébastien Feuillette, Marlène Cassar, +6

Frontiers in Genetics

A Connected Network of Interacting Proteins Is Involved in Human-Tau Toxicity in Drosophila

Sébastien Feuillette, Camille Charbonnier, Thierry Frébourg, +2

Frontiers in Neuroscience