Laëtitia Miguel

Protein Kinase CK-1 Inhibitors As New Potential Drugs for Amyotrophic Lateral Sclerosis

Irene G. Salado, Miriam Redondo, Murilo Lamim Bello et al. · Journal of Medicinal Chemistry · 2014 · 120 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Both cytoplasmic and nuclear accumulations of the protein are neurotoxic in Drosophila models of TDP-43 proteinopathies

Laëtitia Miguel, Thierry Frébourg, Dominique Campion et al. · Neurobiology of Disease · 2010 · 94 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +14

<i>Drosophila</i> models of human tauopathies indicate that Tau protein toxicity <i>in vivo</i> is mediated by soluble cytosolic phosphorylated forms of the protein

Sébastien Feuillette, Laëtitia Miguel, Thierry Frébourg et al. · Journal of Neurochemistry · 2010 · 82 citations

Life Sciences, Neurology, Neuroscience +17

Accumulation of insoluble forms of FUS protein correlates with toxicity in Drosophila

Laëtitia Miguel, Tracey Avequin, Morgane Delarue et al. · Neurobiology of Aging · 2011 · 59 citations

Life Sciences, Entomology, Molecular Biology +4

Impaired SorLA maturation and trafficking as a new mechanism for SORL1 missense variants in Alzheimer disease

Anne Rovelet‐Lecrux, Sébastien Feuillette, Laëtitia Miguel et al. · Acta Neuropathologica Communications · 2021 · 40 citations · Full text

Life Sciences, Genetics, Neurology +14