Lucie Vinklářová

Novel Benzothiazole-Based Ureas as 17β-HSD10 Inhibitors, A Potential Alzheimer’s Disease Treatment

Laura Aitken, Ondřej Benek, Brogan E. McKelvie et al. · Molecules · 2019 · 36 citations · Full text

1-(Benzo[<i>d</i>]thiazol-2-yl)-3-phenylureas as dual inhibitors of casein kinase 1 and ABAD enzymes for treatment of neurodegenerative disorders

Ondřej Benek, Lukáš Hroch, Laura Aitken et al. · Journal of Enzyme Inhibition and Medicinal Chemistry · 2018 · 28 citations · Full text

Drug Target, Structural Scaffold, Pharmacotherapy +19

Benzothiazolyl Ureas are Low Micromolar and Uncompetitive Inhibitors of 17β-HSD10 with Implications to Alzheimer’s Disease Treatment

Monika Schmidt, Ondřej Benek, Lucie Vinklářová et al. · International Journal of Molecular Sciences · 2020 · 21 citations · Full text

Effects of novel 17β-hydroxysteroid dehydrogenase type 10 inhibitors on mitochondrial respiration

Zdeněk Fišar, Kamil Musílek, Ondřej Benek et al. · Toxicology Letters · 2020 · 11 citations

Molecular Pharmacology, Mitochondrial Function, Biochemistry +8

Development of submicromolar 17β-HSD10 inhibitors and their in vitro and in vivo evaluation

Ondřej Benek, Marketa Miskerikova, Monika Schmidt et al. · European Journal of Medicinal Chemistry · 2023 · 11 citations · Full text