IL-17 can promote tumor growth through an IL-6–Stat3 signaling pathway

Lin Wang, Tangsheng Yi, Marcin Kortylewski, +3

The Journal of Experimental Medicine

Bone Marrow NK1.1− and NK1.1+ T Cells Reciprocally Regulate Acute Graft versus Host Disease

Defu Zeng, David B. Lewis, Sussan Dejbakhsh‐Jones, +4

The Journal of Experimental Medicine

Reciprocal differentiation and tissue-specific pathogenesis of Th1, Th2, and Th17 cells in graft-versus-host disease

Tangsheng Yi, Ying Chen, Lin Wang, +11

Blood

Donor CD4+ T and B cells in transplants induce chronic graft-versus-host disease with autoimmune manifestations

Chunyan Zhang, Zhifang Zhang, Yinping Liu, +4

Blood

Absence of donor Th17 leads to augmented Th1 differentiation and exacerbated acute graft-versus-host disease

Tangsheng Yi, Dongchang Zhao, Chia-Lei Lin, +6

Blood

Predominance of NK1.1+TCRαβ+ or DX5+TCRαβ+ T Cells in Mice Conditioned with Fractionated Lymphoid Irradiation Protects Against Graft-Versus-Host Disease: “Natural Suppressor” Cells

Fengshuo Lan, Defu Zeng, Masanori Higuchi, +3

The Journal of Immunology

Cell TherapyAdaptive Immune SystemFractionated IrradiationT-regulatory CellImmunology +14

Cutting Edge: A Role for CD1 in the Pathogenesis of Lupus in NZB/NZW Mice

Defu Zeng, Mi-Kyeong Lee, James W. Tung, +2

The Journal of Immunology

ImmunogeneticsAutoimmune DiseaseLupusImmune Cell DevelopmentT Cells +13

Thymic Damage, Impaired Negative Selection, and Development of Chronic Graft-versus-Host Disease Caused by Donor CD4+ and CD8+ T Cells

Tao Wu, James S. Young, Heather F Johnston, +7

The Journal of Immunology

Cell TherapyLymphocyte DevelopmentT-regulatory CellImmunologyPathology +19

Granulocyte Colony-Stimulating Factor Reduces the Capacity of Blood Mononuclear Cells to Induce Graft-Versus-Host Disease: Impact on Blood Progenitor Cell Transplantation

Defu Zeng, Sussan Dejbakhsh‐Jones, Samuel Strober

Blood

Activation of natural killer T cells in NZB/W mice induces Th1-type immune responses exacerbating lupus

Defu Zeng, Yinping Liu, Stéphane Sidobre, +2

Journal of Clinical Investigation