Akira Ooshima

Probucol prevents the progression of atherosclerosis in Watanabe heritable hyperlipidemic rabbit, an animal model for familial hypercholesterolemia.

T. Kita, Yukio Nagano, Masataka Yokode et al. · Proceedings of the National Academy of Sciences · 1987 · 878 citations · Full text

Vascular Disease, Pathology, Hyperlipidemia +18

Targeted disruption of TGF-β1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction

Misako Sato, Yasuteru Muragaki, Shizuya Saika et al. · Journal of Clinical Investigation · 2003 · 744 citations · Full text

Targeted disruption of TGF-β1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction

Misako Sato, Yasuteru Muragaki, Shizuya Saika et al. · Journal of Clinical Investigation · 2003 · 673 citations

Renal Pathology, Renal Inflammation, Pathology +20

Blockade of type β transforming growth factor signaling prevents liver fibrosis and dysfunction in the rat

Zhe Qi, Nobuhiko Atsuchi, Akira Ooshima et al. · Proceedings of the National Academy of Sciences · 1999 · 289 citations · Full text

Smad3 Signaling Is Required for Epithelial-Mesenchymal Transition of Lens Epithelium after Injury

Shizuya Saika, Satoko Kono-Saika, Yoshitaka Ohnishi et al. · American Journal Of Pathology · 2004 · 284 citations · Full text

Regenerative Medicine, Epithelial-mesenchymal Transition, Ocular Disease +11