Lytic Granule Loading of CD8+ T Cells Is Required for HIV-Infected Cell Elimination Associated with Immune Control

Stephen A. Migueles, Christine Osborne, Cassandra Royce, +25

Immunity

Human RetrovirusImmunologyLytic Granule LoadingAntiviral ResponseAutoimmunity +9

Enhanced Effector Responses in Activated CD8+ T Cells Deficient in Diacylglycerol Kinases

Matthew J. Riese, Liang‐Chuan S. Wang, Edmund K. Moon, +5

Cancer Research

ImmunologyImmune RegulationImmunoeditingImmunologic MechanismCar Activity +20

Spatial proteomic characterization of HER2-positive breast tumors through neoadjuvant therapy predicts response

Katherine McNamara, Jennifer L. Caswell‐Jin, Rohan P. Joshi, +12

Nature Cancer

Breast OncologyOncologyEndocrine-related CancerNeoadjuvant TherapyMedicine +7

The ζ Isoform of Diacylglycerol Kinase Plays a Predominant Role in Regulatory T Cell Development and TCR-Mediated Ras Signaling

Rohan P. Joshi, Amanda M. Schmidt, Jayajit Das, +7

Science Signaling

T-regulatory CellImmunologyImmune RegulationT CellsTcr-stimulated Ras Activation +15

A predictive tool for identification of SARS-CoV-2 PCR-negative emergency department patients using routine test results

Rohan P. Joshi, Vikas Pejaver, Noah Hammarlund, +16

Journal of Clinical Virology

Viral DiagnosticsRoutine Test ResultsDiagnostic TestCovid-19 PandemicDiagnosis +6

Loss of PIKfyve in platelets causes a lysosomal disease leading to inflammation and thrombosis in mice

Sang Hee Min, Aae Suzuki, Timothy J. Stalker, +14

Nature Communications

ImmunologyBlood CellPathologyCell DeathInflammation +14

Tremelimumab and durvalumab as neoadjuvant or non-operative management strategy of patients with microsatellite instability-high resectable gastric or gastroesophageal junction adenocarcinoma: the INFINITY study by GONO

A. Raimondi, Sara Lonardi, Sabina Murgioni, +47

Annals of Oncology

Surgical OncologyEsophageal CancerGastrointestinal OncologyMedicineInfinity Study +8

Diacylglycerol Kinase ζ Limits the Generation of Natural Regulatory T Cells

Amanda M. Schmidt, Tao Zou, Rohan P. Joshi, +4

Science Signaling

Targeted deep sequencing of cell‐free DNA in serous body cavity fluids with malignant, suspicious, and benign cytology

Soo‐Ryum Yang, Kelly L. Mooney, Paolo Libiran, +9

Cancer Cytopathology

Multiplexed detection of viral infections using rapid <i>in situ</i> RNA analysis on a chip

Sydney M. Shaffer, Rohan P. Joshi, Benjamin S. Chambers, +8

Lab on a Chip