Michael E. Harbour

Mutation in VPS35 associated with Parkinson’s disease impairs WASH complex association and inhibits autophagy

Eszter Zavodszky, Matthew Seaman, Kévin Moreau et al. · Nature Communications · 2014 · 450 citations · Full text

Membrane recruitment of the cargo-selective retromer subcomplex is catalysed by the small GTPase Rab7 and inhibited by the Rab-GAP TBC1D5

Matthew Seaman, Michael E. Harbour, Daniel Tattersall et al. · Journal of Cell Science · 2009 · 377 citations · Full text

Rab Gap Family, Signal Recognition, Molecular Biology +16

The cargo-selective retromer complex is a recruiting hub for protein complexes that regulate endosomal tubule dynamics

Michael E. Harbour, Sophia Y. Breusegem, Robin Antrobus et al. · Journal of Cell Science · 2010 · 248 citations · Full text

Molecular Biology, Molecular Genetics, Cytoskeleton +20

The AAA+ protein ATAD3 has displacement loop binding properties and is involved in mitochondrial nucleoid organization

Jiuya He, Chih-Chieh Mao, Aurelio Reyes et al. · The Journal of Cell Biology · 2007 · 233 citations · Full text

Chromatin, Mitochondrial Biogenesis, Mitochondrial Function +15

Recruitment of the endosomal WASH complex is mediated by the extended ‘tail’ of Fam21 binding to the retromer protein Vps35

Michael E. Harbour, Sophia Y. Breusegem, Matthew Seaman · Biochemical Journal · 2011 · 230 citations