Sophia Y. Breusegem

Mutation in VPS35 associated with Parkinson’s disease impairs WASH complex association and inhibits autophagy

Eszter Zavodszky, Matthew Seaman, Kévin Moreau et al. · Nature Communications · 2014 · 468 citations · Full text

Life Sciences, Cell Biology, Neuroscience +17

The cargo-selective retromer complex is a recruiting hub for protein complexes that regulate endosomal tubule dynamics

Michael E. Harbour, Sophia Y. Breusegem, Robin Antrobus et al. · Journal of Cell Science · 2010 · 249 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Recruitment of the endosomal WASH complex is mediated by the extended ‘tail’ of Fam21 binding to the retromer protein Vps35

Michael E. Harbour, Sophia Y. Breusegem, Matthew Seaman · Biochemical Journal · 2011 · 240 citations

Life Sciences, Cell Biology, Molecular Biology +17

Regulation of rat intestinal Na-dependent phosphate transporters by dietary phosphate

Héctor Giral, Yupanqui Caldas, Eileen Sutherland et al. · American Journal of Physiology-Renal Physiology · 2009 · 152 citations · Full text

Medicine, Pharmacology, Physiology +17

Different ways to die: cell death modes of the unicellular chlorophyte Dunaliella viridis exposed to various environmental stresses are mediated by the caspase-like activity DEVDase

Carlos Jiménez, Juan M. Capasso, Charles L. Edelstein et al. · Journal of Experimental Botany · 2009 · 128 citations · Full text

Life Sciences, Cell Biology, Apoptosis +7