Tova Chajek‐Shaul

Mechanism of hypertriglyceridemia in human apolipoprotein (apo) CIII transgenic mice. Diminished very low density lipoprotein fractional catabolic rate associated with increased apo CIII and reduced apo E on the particles.

Katriina Aalto‐Setälä, Edward A. Fisher, X Chen et al. · Journal of Clinical Investigation · 1992 · 455 citations · Full text

Hyperlipidemia, Low Density, Oxidative Stress +19

Transgenic expression of mammalian heparanase uncovers physiological functions of heparan sulfate in tissue morphogenesis, vascularization, and feeding behavior

Eyal Zcharia, Shula Metzger, Tova Chajek‐Shaul et al. · The FASEB Journal · 2004 · 246 citations

Human Heparanase, Embryology, Hpa-tg Mice +17

Lipoprotein lipase expression exclusively in liver. A mouse model for metabolism in the neonatal period and during cachexia.

Martin Merkel, Peter Weinstock, Tova Chajek‐Shaul et al. · Journal of Clinical Investigation · 1998 · 133 citations · Full text

Liver Lpl, Fatty Liver Disease, Oxidative Stress +17

Hypertriglyceridemia and cholesteryl ester transfer protein interact to dramatically alter high density lipoprotein levels, particle sizes, and metabolism. Studies in transgenic mice.

Tony Hayek, Neal Azrolan, Roy B. Verdery et al. · Journal of Clinical Investigation · 1993 · 131 citations · Full text

Metabolic Syndrome, Hdl Ce Tr, Lipid Synthesis +15

An interaction between the human cholesteryl ester transfer protein (CETP) and apolipoprotein A-I genes in transgenic mice results in a profound CETP-mediated depression of high density lipoprotein cholesterol levels.

Tony Hayek, Tova Chajek‐Shaul, A Walsh et al. · Journal of Clinical Investigation · 1992 · 122 citations · Full text

Genetics, Lipid Peroxidation, Hucetptg Hdl +17