Kathleen Hehir

Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia

Marina Cavazzana, Emmanuel Payen, Olivier Nègre et al. · Nature · 2010 · 1.3K citations

Hmga2 Activation, Transfusion Independence, Genetics +7

New Helper Cells and Matched Early Region 1-Deleted Adenovirus Vectors Prevent Generation of Replication-Competent Adenoviruses

Frits J. Fallaux, A. Bout, Ietje van der Velde et al. · Human Gene Therapy · 1998 · 475 citations

Viral Replication, New Helper Cells, Molecular Virology +14

Expression and characterization of the cystic fibrosis transmembrane conductance regulator

Richard J. Gregory, Seng H. Cheng, Devra P. Rich et al. · Nature · 1990 · 343 citations

Protein Secretion, Signal Transduction, Molecular Physiology +11

Development and Analysis of Recombinant Adenoviruses for Gene Therapy of Cystic Fibrosis

Devra P. Rich, Larry A. Couture, Lisa Cardoza et al. · Human Gene Therapy · 1993 · 163 citations

An engineered intersubunit disulfide enhances the stability and DNA binding of the N-terminal domain of .lambda. repressor

Robert T. Sauer, Kathleen Hehir, Robert S. Stearman et al. · Biochemistry · 1986 · 149 citations