Katherine A. Alexander

TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion

Omar Khan, Josephine R. Giles, Sierra McDonald et al. · Nature · 2019 · 1.5K citations

Transcriptional Regulation, T-regulatory Cell, Gene Expression +3

Disruption of TET2 promotes the therapeutic efficacy of CD19-targeted T cells

Joseph A. Fraietta, Christopher L. Nobles, Morgan A. Sammons et al. · Nature · 2018 · 829 citations · Full text

Cd19-targeted T Cells, Cancer Immunosurveillance, Immunology +8

Dendritic Cell Paucity Leads to Dysfunctional Immune Surveillance in Pancreatic Cancer

Samarth Hegde, Varintra E. Krisnawan, Brett H. Herzog et al. · Cancer Cell · 2020 · 442 citations · Full text

Cancer Immunosurveillance, Pancreatic Cancer, Immunology +10

An NK-like CAR T cell transition in CAR T cell dysfunction

Charly R. Good, M. Ángela Aznar, Shunichiro Kuramitsu et al. · Cell · 2021 · 376 citations · Full text

Autoimmune Disease, T-regulatory Cell, Immunology +7

Genetically engineered myeloid cells rebalance the core immune suppression program in metastasis

Sabina Kaczanowska, Daniel W. Beury, Vishaka Gopalan et al. · Cell · 2021 · 188 citations · Full text

Immunology, Myelopoiesis, Autoimmunity +6