An NK-like CAR T cell transition in CAR T cell dysfunction

Charly R. Good, M. Ángela Aznar, Shunichiro Kuramitsu, +27

Cell

Autoimmune DiseaseT-regulatory CellImmunologyAutoimmunityCellular Immune Response +5

Impaired Death Receptor Signaling in Leukemia Causes Antigen-Independent Resistance by Inducing CAR T-cell Dysfunction

Nathan Singh, Yong Gu Lee, Olga Shestova, +19

Cancer Discovery

TET1-Mediated Hypomethylation Activates Oncogenic Signaling in Triple-Negative Breast Cancer

Charly R. Good, Shoghag Panjarian, Andrew D. Kelly, +4

Cancer Research

Deletion of the inhibitory co-receptor CTLA-4 enhances and invigorates chimeric antigen receptor T cells

Sangya Agarwal, M. Ángela Aznar, Andrew J. Rech, +17

Immunity

p53 mediates target gene association with nuclear speckles for amplified RNA expression

Katherine A. Alexander, Allison Coté, Son C. Nguyen, +15

Molecular Cell

Transcriptional RegulationGene AssociationGeneticsRna BiologyGene Regulation +6

A novel isoform of TET1 that lacks a CXXC domain is overexpressed in cancer

Charly R. Good, Jozef Madžo, Bela Patel, +4

Nucleic Acids Research

Epigenetic ChangeGeneticsDna MethylationPathologyCancer Biology +23

Reverse Transcriptase Inhibition Disrupts Repeat Element Life Cycle in Colorectal Cancer

Mihir Rajurkar, Aparna R. Parikh, Alexander Solovyov, +46

Cancer Discovery

Radiation OncologyEngineeringOncogenic AgentMedicineColorectal Cancer +10

Reverse Transcriptase Inhibition Disrupts Repeat Element Life Cycle in Colorectal Cancer.

Mihir Rajurkar, Aparna R. Parikh, Eunae You, +44

PubMed

TOX2 coordinates with TET2 to positively regulate central memory differentiation in human CAR T cells

Sierra M. Collins, Katherine A. Alexander, Stefan Lundh, +5

Science Advances

Histone acetylation in an Alzheimer’s disease cell model promotes homeostatic amyloid-reducing pathways

Daniel C. Xu, Hanna Sas‐Nowosielska, Greg Donahue, +4

Acta Neuropathologica Communications