Filippo Minutolo

Increased Lactate Secretion by Cancer Cells Sustains Non-cell-autonomous Adaptive Resistance to MET and EGFR Targeted Therapies

Maria Apicella, Elisa Giannoni, Stephany Fiore et al. · Cell Metabolism · 2018 · 271 citations · Full text

Medicine, Egfr Targeted Therapies, Lactate Secretion +10

Discovery of <i>N</i>-Hydroxyindole-Based Inhibitors of Human Lactate Dehydrogenase Isoform A (LDH-A) as Starvation Agents against Cancer Cells

Carlotta Granchi, Sarabindu Roy, Chiara Giacomelli et al. · Journal of Medicinal Chemistry · 2011 · 215 citations · Full text

Bioorganic Chemistry, Aldo-keto Reductase, Metabolic Remodeling +19

Synergistic interaction of novel lactate dehydrogenase inhibitors with gemcitabine against pancreatic cancer cells in hypoxia

Mina Maftouh, Abolfazl Avan, Rocco Sciarrillo et al. · British Journal of Cancer · 2013 · 172 citations · Full text

Heterogeneous asymmetric epoxidation of unfunctionalized olefins catalyzed by polymer-bound (salen)manganese complexes

Filippo Minutolo, Dario Pini, Antonella Petri et al. · Tetrahedron Asymmetry · 1996 · 144 citations

Inorganic Chemistry, Chemical Engineering, Engineering +9

Identification of LDH-A as a therapeutic target for cancer cell killing via (i) p53/NAD(H)-dependent and (ii) p53-independent pathways

Simon J. Allison, John R. P. Knight, Carlotta Granchi et al. · Oncogenesis · 2014 · 141 citations · Full text