Katie Ellard

Small Molecule Inhibitors of the Neuropilin-1 Vascular Endothelial Growth Factor A (VEGF-A) Interaction

Ashley Jarvis, C.K. Allerston, Haiyan Jia et al. · Journal of Medicinal Chemistry · 2010 · 194 citations · Full text

Small Molecule Inhibitors, Endothelial Cells, Small Molecule Design +18

A selective inhibitor reveals PI3Kγ dependence of TH17 cell differentiation

Giovanna Bergamini, Kathryn M. Bell, Satoko Shimamura et al. · Nature Chemical Biology · 2012 · 143 citations

Signal Transduction, Signaling Pathway, Cell Regulation +7

SAR studies around a series of triazolopyridines as potent and selective PI3Kγ inhibitors

Kathryn M. Bell, Mihiro Sunose, Katie Ellard et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 48 citations · Full text

Molecular Pharmacology, Pharmaceutical Science, Selective Pi3kγ Inhibitors +12

Discovery of 5-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-N-(tert-butyl)pyridine-3-sulfonamide (CZC24758), as a potent, orally bioavailable and selective inhibitor of PI3K for the treatment of inflammatory disease

Mihiro Sunose, Kathryn Bell, Katie Ellard et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 24 citations · Full text

Inflammation, Medicinal Chemistry, Anti-inflammatory +9

Discovery of novel PI3Kγ/δ inhibitors as potential agents for inflammation

Katie Ellard, Mihiro Sunose, Kathryn Bell et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 18 citations · Full text

Inflammation, Molecular Pharmacology, Novel Pi3kγ/δ Inhibitors +10