Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure

Stéphane Heymans, Aernout Luttun, Dieter Nuyens, +20

Nature Medicine

CardiomyopathyHeart FailureCardiovascular DiseasePlasminogen ActivatorsMedicine +9

The mechanism of γ-Secretase dysfunction in familial Alzheimer disease

Lucía Chávez‐Gutiérrez, Leen Bammens, Iryna Benilova, +15

The EMBO Journal

Neurodegenerative Diseasesγ-Secretase DysfunctionAlzheimer's DiseaseDegenerative PathologyNeurology +4

The Neural Cell Adhesion Molecules L1 and CHL1 Are Cleaved by BACE1 Protease in Vivo

Lujia Zhou, Soraia Barão, Mathias Laga, +8

Journal of Biological Chemistry

Bace1 ProteaseCell AdhesionSynaptic TransmissionMolecular BiologyNeurochemical Biomarkers +28

Acute function of secreted amyloid precursor protein fragment APPsα in synaptic plasticity

Meike Hick, Ulrike Herrmann, Sascha W. Weyer, +10

Acta Neuropathologica

Neurodegenerative DiseasesSynaptic PlasticityMolecular NeuroscienceSynaptic NeuroscienceSynaptic Transmission +9

Influence of the Anthelmintic Mebendazole on Microtubules and Intracellular Organelle Movement in Nematode Intestinal Cells

M. Borgers, Sonja De Nollin, M. De Brabander, +1

American Journal of Veterinary Research

Antiparasitic AgentCytoskeletonCellular PhysiologyAnthelmintic MebendazoleParasitology +14

Using Human iPSC-Derived Neurons to Model TAU Aggregation

An Verheyen, Annick Diels, Joyce Dijkmans, +8

PLoS ONE

MitophagyNeurochemical BiomarkersSynaptic SignalingRobust Tau AggregationTau Aggregation +16

Dedifferentiated cardiomyocytes from chronic hibernating myocardium are ischemia-tolerant

Jannie Ausma, F. Thoné, G Dispersyn, +4

Molecular and Cellular Biochemistry

Cardiac MuscleCardiomyopathyHeart FailurePhysiologyMedicine +2

Beta-cyclodextrins as vehicles in eye-drop formulations: an evaluation of their effects on rabbit corneal epithelium.

Thomas Jansen, Benoit Xhonneux, J Mesens, +1

PubMed

Medicinal ChemistryElectron MicroscopyOphthalmologyCyclic MoleculesMedicine +10

A new method to study activated oxygen species induced damage in cardiomyocytes and protection by Ca2+-Antagonists

Luc Ver Donck, Jos L. H. Van Reempts, G Vandeplassche, +1

Journal of Molecular and Cellular Cardiology

Cardiac MuscleCardiomyopathyHeart FailureBiochemistryMedicine +8

Morphological Changes in Cysticerci of Taenia taeniaeformis after Mebendazole Treatment

M. Borgers, Sonja De Nollin, A. Verheyen, +2

Journal of Parasitology

Morphological ChangesParasitic ProtozoaPathogenesisHistopathologyImmunology +10