Aswath P. Chandrasekar

Reactivating latent HIV with PKC agonists induces resistance to apoptosis and is associated with phosphorylation and activation of BCL2

Andrea French, Sekar Natesampillai, Ashton Krogman et al. · PLoS Pathogens · 2020 · 40 citations · Full text

Life Sciences, Cell Biology, Immunology +17

The BCL-2 Inhibitor Venetoclax Augments Immune Effector Function Mediated by Fas Ligand, TRAIL, and Perforin/Granzyme B, Resulting in Reduced Plasma Viremia and Decreased HIV Reservoir Size during Acute HIV Infection in a Humanized Mouse Model

Aswath P. Chandrasekar, Nathan W. Cummins, Sekar Natesampillai et al. · Journal of Virology · 2022 · 25 citations · Full text

Life Sciences, Immunology, Infectious Diseases +17

The Combination of Venetoclax and Ixazomib Selectively and Efficiently Kills HIV-Infected Cell Lines but Has Unacceptable Toxicity in Primary Cell Models

Alecia Alto, Sekar Natesampillai, Aswath P. Chandrasekar et al. · Journal of Virology · 2021 · 19 citations · Full text

Life Sciences, Infectious Diseases, Pharmacology +17