Rhizoma Coptidis alkaloids alleviate hyperlipidemia in B6 mice by modulating gut microbiota and bile acid pathways

Kai He, Yinran Hu, Hang Ma, +6

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Rhizoma Coptidis AlkaloidsDysbiosisBiochemistryMedicineLipid Peroxidation +6

Activation of Akt and JNK/Nrf2/NQO1 pathway contributes to the protective effect of coptisine against AAPH-induced oxidative stress

Yinran Hu, Hang Ma, Zongyao Zou, +6

Biomedicine & Pharmacotherapy

InflammationAnti-inflammatoryAaph-induced Oxidative StressAutoimmune DiseaseAllergy +9

Coptisine attenuates obesity-related inflammation through LPS/TLR-4-mediated signaling pathway in Syrian golden hamsters

Zongyao Zou, Yinran Hu, Hang Ma, +7

Fitoterapia

ObesityMetabolic SyndromeInflammationCytokineAnti-inflammatory +10

Hypolipidemic Effects of Alkaloids from Rhizoma Coptidis in Diet-Induced Hyperlipidemic Hamsters

Kai He, Shuming Kou, Zongyao Zou, +5

Planta Medica

Molecular PharmacologySerum Total CholesterolOxysterolDiet-induced Hyperlipidemic HamstersBiochemistry +12

Antihyperglycemia and Antihyperlipidemia Effect of Protoberberine Alkaloids From Rhizoma Coptidis in HepG2 Cell and Diabetic KK‐Ay Mice

Hang Ma, Yinran Hu, Zongyao Zou, +3

Drug Development Research

Diabetic Kk‐ay MiceLipid PeroxidationCoptis Chinensis FranchGlucose ToleranceInsulin Signaling +14

The Safety and Anti‐Hypercholesterolemic Effect of Coptisine in Syrian Golden Hamsters

Kai He, Xiaoli Ye, Hao Wu, +7

Lipids

HyperlipidemiaOxidative StressInflammationMetabolic SyndromeSyrian Golden Hamsters +16

Comparative effect of berberine and its derivative 8-cetylberberine on attenuating atherosclerosis in ApoE−/− mice

Min Feng, Zongyao Zou, Xia Zhou, +5

International Immunopharmacology

InflammationBiochemistryComparative EffectApoe−/− MiceMedicine +7

The protective effect of coptisine on experimental atherosclerosis ApoE−/− mice is mediated by MAPK/NF-κB-dependent pathway

Min Feng, Shuzhen Kong, Zhen-Xu Wang, +6

Biomedicine & Pharmacotherapy

InflammationAnti-inflammatoryCell SignalingMedicineImmunology +10

Epiberberine reduces serum cholesterol in diet-induced dyslipidemia Syrian golden hamsters via network pathways involving cholesterol metabolism

Zongyao Zou, Yinran Hu, Hang Ma, +3

European Journal of Pharmacology

Metabolic SyndromeCholesterol MetabolismLipid DisorderSerum CholesterolBiochemistry +10

Purification of α‐glucosidase from mouse intestine by countercurrent chromatography coupled with a reverse micelle solvent system

Kai He, Zongyao Zou, Yinran Hu, +5

Journal of Separation Science

EngineeringGlycobiologyPolysaccharideDigestive TractEnzymatic Modification +17