Immunogenicity of Murine Solid Tumor Models as a Defining Feature of In Vivo Behavior and Response to Immunotherapy

Melissa G. Lechner, Saman S. Karimi, Keegan Barry-Holson, +6

Journal of Immunotherapy

T-regulatory CellImmunologyImmune RegulationPathologyImmunoediting +22

Gene Therapy for Hemophilia B: Host Immunosuppression Prolongs the Therapeutic Effect of Adenovirus-Mediated Factor IX Expression

B Fang, Randy C. Eisensmith, H. Wang, +9

Human Gene Therapy

Pivotal Study of Iodine-131–Labeled Chimeric Tumor Necrosis Treatment Radioimmunotherapy in Patients With Advanced Lung Cancer

Shaoliang Chen, Like Yu, Changying Jiang, +13

Journal of Clinical Oncology

Generation of Rituximab Polymer May Cause Hyper-Cross-linking–Induced Apoptosis in Non-Hodgkin's Lymphomas

Nan Zhang, Leslie A. Khawli, Peisheng Hu, +1

Clinical Cancer Research

New FormulationApoptosisImmunologyCell DeathImmunotherapeutics +16

Costimulation of type-2 innate lymphoid cells by GITR promotes effector function and ameliorates type 2 diabetes

Lauriane Galle-Treger, Ishwarya Sankaranarayanan, Benjamin P. Hurrell, +13

Nature Communications

Complete regression of experimental solid tumors by combination LEC/chTNT-3 immunotherapy and CD25(+) T-cell depletion.

Jiali Li, Peisheng Hu, Leslie A. Khawli, +1

PubMed

ImmunologyImmunologic MechanismImmunotherapeuticsImmune Cell TherapyImmunotherapy +18

Comparison of three different targeted tissue factor fusion proteins for inducing tumor vessel thrombosis.

Peisheng Hu, Jianghua Yan, Jahangir Sharifi, +3

PubMed

ImmunologyPathologyTumor BiologyThrombosisAngiogenesis +16

A New Chemically Modified Chimeric TNT-3 Monoclonal Antibody Directed Against DNA for the Radioimmunotherapy of Solid Tumors

Jason L. Hornick, Jahangir Sharifi, Leslie A. Khawli, +6

Cancer Biotherapy and Radiopharmaceuticals

Solid TumorsImmunologyPathologyImmunotherapyTumor Biology +15

A Therapeutic OX40 Agonist Dynamically Alters Dendritic, Endothelial, and T Cell Subsets within the Established Tumor Microenvironment

Angela D. Pardee, Dustin McCurry, Sean Alber, +3

Cancer Research

Pretreatment with a monoclonal antibody/interleukin-2 fusion protein directed against DNA enhances the delivery of therapeutic molecules to solid tumors.

Jason L. Hornick, Leslie A. Khawli, Peisheng Hu, +3

PubMed

Solid TumorsNitric OxideImmunologyImmunoeditingImmunotherapy +15