Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies

Chetan Bettegowda, Mark Sausen, Rebecca Leary, +60

Science Translational Medicine

Dna AnalysisPathologyVarious Cancer TypesNucleic Acid BiomarkersTumor Biology +15

Direct detection of early-stage cancers using circulating tumor DNA

Jillian Phallen, Mark Sausen, Vilmos Adleff, +34

Science Translational Medicine

EngineeringDirect DetectionPathologyNucleic Acid BiomarkersCancer Detection +14

Amplification of the <i>MET</i> Receptor Drives Resistance to Anti-EGFR Therapies in Colorectal Cancer

Alberto Bardelli, Simona Corso, Andrea Bertotti, +25

Cancer Discovery

EngineeringPathologyCancer BiologyTumor BiologyCancer Cell Biology +15

Detection of Chromosomal Alterations in the Circulation of Cancer Patients with Whole-Genome Sequencing

Rebecca Leary, Mark Sausen, Isaac Kinde, +9

Science Translational Medicine

Healthy SubjectsGeneticsPathologyCancer PatientsPlasma Dna +15

Mutations in <i>CIC</i> and <i>FUBP1</i> Contribute to Human Oligodendroglioma

Chetan Bettegowda, Nishant Agrawal, Yuchen Jiao, +15

Science

ChromatinNeuro-oncologyDevelopmental BiologySomatic VariantGlioma +12

The genomic landscape of response to EGFR blockade in colorectal cancer

Andrea Bertotti, Eniko Papp, Siân Jones, +32

Nature

OncologyGenomic LandscapeMedicinePathologyColorectal Cancer +7

Detection of somatic mutations and HPV in the saliva and plasma of patients with head and neck squamous cell carcinomas

Yuxuan Wang, Simeon Springer, Carolyn L. Mulvey, +29

Science Translational Medicine

Clinical implications of genomic alterations in the tumour and circulation of pancreatic cancer patients

Mark Sausen, Jillian Phallen, Vilmos Adleff, +23

Nature Communications

DETECTION OF CIRCULATING TUMOR DNA IN EARLY AND LATE STAGE HUMAN MALIGNANCIES

Chetan Bettegowda, Mark Sausen, Robert Leary, +8

Neuro-Oncology

Minimally-invasive MethodsDna AnalysisPathologyHigh-grade GliomasGlioma +18

Personalized genomic analyses for cancer mutation discovery and interpretation

Siân Jones, Valsamo Anagnostou, Karli Lytle, +15

Science Translational Medicine

EngineeringGeneticsPathologyTumor BiologyTumor Heterogeneity +14