Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor

Naftaly Meydan, T Grunberger, Harjit Dadi, +9

Nature

Hematological MalignancyMalignant Blood DisorderImmunologyHematologyMedicine +2

Crystal Structure of Hck in Complex with a Src Family–Selective Tyrosine Kinase Inhibitor

Thomas H. Schindler, Frank Sicheri, Alexander R. Pico, +3

Molecular Cell

Crystal StructureBiochemistryNatural SciencesReceptor Tyrosine KinaseProtein X-ray Crystallography +4

Flk-1 as a target for tumor growth inhibition.

L M Strawn, Gerald McMahon, Harald App, +15

PubMed

Endothelial CellsCancer BiologyTumor BiologyAngiogenesisReceptor Tyrosine Kinase +16

The effect of tyrosine-specific protein phosphorylation on the assembly of adherens-type junctions.

Tova Volberg, Yehiel Zick, Ron O. Dror, +4

The EMBO Journal

Signal TransductionTyrosine-specific Protein PhosphorylationBiochemistryNatural SciencesCell Adhesion +7

Tyrphostins Inhibit Epidermal Growth Factor (EGF)-Receptor Tyrosine Kinase Activity in Living Cells and EGF-Stimulated Cell Proliferation

R. Lyall, Asher Zilberstein, Aviv Gazit, +3

Journal of Biological Chemistry

Living CellsSignal TransductionSignaling PathwayGrowth FactorMedicine +13

Tyrphostin-induced inhibition of p210bcr-abl tyrosine kinase activity induces K562 to differentiate

Mordechai Anafi, Aviv Gazit, A. Zehavi, +2

Blood

Tyrphostins inhibit PDGF-induced DNA synthesis and associated early events in smooth muscle cells

Glenda E. Bilder, J Krawiec, Karen McVety, +7

American Journal of Physiology-Cell Physiology

Cell ProliferationCytoskeletonCellular PhysiologyReceptor Tyrosine KinaseCell Signaling +16

Potential 18F-labeled biomarkers for epidermal growth factor receptor tyrosine kinase

Thomas A. Bonasera, Giuseppina Ortu, Yulia Rozen, +6

Nuclear Medicine and Biology

Signal TransductionSignaling PathwayPotential 18F-labeled BiomarkersMedicineBiomarker Target +8

Enhancement of chemosensitivity by tyrphostin AG825 in high-p185(neu) expressing non-small cell lung cancer cells.

Chun‐Ming Tsai, A Levitzki, Li‐Hwa Wu, +4

PubMed

Tumor BiologyMedicinePharmacologyTyrphostin Ag825Cell Lines +10

Tyrphostin induced growth inhibition: correlation with effect on p210bcr-abl autokinase activity in K562 chronic myelogenous leukemia.

Gurmeet Kaur, Aviv Gazit, A Levitzki, +3

PubMed

Myelogenous LeukemiaImmunologyTumor BiologyMyeloid NeoplasiaHematological Malignancy +15