Nadine Ruecker

Genome-wide gene expression tuning reveals diverse vulnerabilities of M. tuberculosis

Barbara Bosch, Michael A. DeJesus, Nicholas C. Poulton et al. · Cell · 2021 · 312 citations · Full text

CRISPRi chemical genetics and comparative genomics identify genes mediating drug potency in Mycobacterium tuberculosis

Shuqi Li, Nicholas C. Poulton, Jesseon S. Chang et al. · Nature Microbiology · 2022 · 211 citations · Full text

Large-scale chemical–genetics yields new M. tuberculosis inhibitor classes

Eachan O. Johnson, Emily LaVerriere, Emma Office et al. · Nature · 2019 · 173 citations · Full text

Medicinal Chemistry, Antimicrobial Drug Discovery, Pulmonary Tuberculosis +9

Fumarase Deficiency Causes Protein and Metabolite Succination and Intoxicates Mycobacterium tuberculosis

Nadine Ruecker, Robert S. Jansen, Carolina Trujillo et al. · Cell chemical biology · 2017 · 57 citations · Full text

Pulmonary Tuberculosis, Pathogenesis, Intoxicates Mycobacterium Tuberculosis +8

Chemical–genetic interaction mapping links carbon metabolism and cell wall structure to tuberculosis drug efficacy

Eun‐Ik Koh, Peter O. Oluoch, Nadine Ruecker et al. · Proceedings of the National Academy of Sciences · 2022 · 38 citations · Full text

Drug Target, Tuberculosis Prevention, Cell Wall Structure +28