Cheng Liao

RN486, a Selective Bruton's Tyrosine Kinase Inhibitor, Abrogates Immune Hypersensitivity Responses and Arthritis in Rodents

Daigen Xu, Yong Kim, Jennifer Postelnek et al. · Journal of Pharmacology and Experimental Therapeutics · 2012 · 141 citations

Medicine, Immunology, Pharmacology +17

3-Amido Pyrrolopyrazine JAK Kinase Inhibitors: Development of a JAK3 vs JAK1 Selective Inhibitor and Evaluation in Cellular and in Vivo Models

Michael Soth, Johannes C. Hermann, Calvin Yee et al. · Journal of Medicinal Chemistry · 2012 · 66 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Rational Design of Highly Selective Spleen Tyrosine Kinase Inhibitors

Matthew C. Lucas, David Goldstein, Johannes C. Hermann et al. · Journal of Medicinal Chemistry · 2012 · 49 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Selective inhibition of spleen tyrosine kinase (SYK) with a novel orally bioavailable small molecule inhibitor, RO9021, impinges on various innate and adaptive immune responses: implications for SYK inhibitors in autoimmune disease therapy

Cheng Liao, Jonathan Hsu, Yong Kim et al. · Arthritis Research & Therapy · 2013 · 46 citations · Full text

Medicine, Immunology, Pharmacology +17

Pyrrolopyrazines as Selective Spleen Tyrosine Kinase Inhibitors

Fernando Padilla, Niala Bhagirath, Shaoqing Chen et al. · Journal of Medicinal Chemistry · 2013 · 40 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13