KLHL3 mutations cause familial hyperkalemic hypertension by impairing ion transport in the distal nephron

Hélène Louis-Dit-Picard, Julien Barc, Daniel Trujillano, +35

Nature Genetics

Ion TransportHypertonicityUrologyHypertensionMolecular Physiology +7

Conditional Mineralocorticoid Receptor Expression in the Heart Leads to Life-Threatening Arrhythmias

Antoine Ouvrard‐Pascaud, Yannis Sainte–Marie, Jean‐Pierre Bénitah, +16

Circulation

<i>WNK1</i> -related Familial Hyperkalemic Hypertension results from an increased expression of L-WNK1 specifically in the distal nephron

Emmanuelle Vidal‐Petiot, Emilie Elvira‐Matelot, Kerim Mutig, +10

Proceedings of the National Academy of Sciences

Decreased ENaC expression compensates the increased NCC activity following inactivation of the kidney-specific isoform of WNK1 and prevents hypertension

Juliette Hadchouel, Christelle Soukaseum, Cara Büsst, +8

Proceedings of the National Academy of Sciences

WNK-SPAK-NCC Cascade Revisited

María Chávez‐Canales, Chong Zhang, Christelle Soukaseum, +13

Hypertension

EngineeringNetwork AnalysisCellular PhysiologyBlood PressureWnk-spak-ncc Cascade +16

Cross-Talk Between Mineralocorticoid and Angiotensin II Signaling for Cardiac Remodeling

An Di Zhang, Aurélie Nguyen Dinh Cat, Christelle Soukaseum, +6

Hypertension

Cardiac MuscleHypertensionHeart FailureAngiotensin IiCardiomyopathy +13

Conditional glucocorticoid receptor expression in the heart induces atrio‐ventricular block

Yannis Sainte–Marie, Aurelie Nguyen Dinh Cat, Romain Perrier, +8

The FASEB Journal

Cardiac MuscleHypertensionHeart FailureCardiomyopathyCardiovascular Disease +13

A mouse model of pseudohypoaldosteronism type II reveals a novel mechanism of renal tubular acidosis

Karen I. López‐Cayuqueo, María Chávez‐Canales, Alexia Pillot, +12

Kidney International

A fate-mapping approach reveals the composite origin of the connecting tubule and alerts on “single-cell”-specific KO model of the distal nephron

Francesco Trepiccione, Christelle Soukaseum, Anna Iervolino, +6

American Journal of Physiology-Renal Physiology

Acute genetic ablation of pendrin lowers blood pressure in mice

Francesco Trepiccione, Christelle Soukaseum, Véronique Baudrie, +10

Nephrology Dialysis Transplantation