Keyi Tang

<scp>TGF‐β</scp>‐induced <scp>PI3K</scp>/<scp>AKT</scp>/<scp>mTOR</scp> pathway controls myofibroblast differentiation and secretory phenotype of valvular interstitial cells through the modulation of cellular senescence in a naturally occurring in vitro canine model of myxomatous mitral valve disease

Qiyu Tang, Greg Markby, Andrew J. MacNair et al. · Cell Proliferation · 2023 · 66 citations · Full text

Life Sciences, Cardiology, Molecular Biology +15

Autophagy regulates cellular senescence by mediating the degradation of CDKN1A/p21 and CDKN2A/p16 through SQSTM1/p62-mediated selective autophagy in myxomatous mitral valve degeneration

Qiyu Tang, Keyi Tang, Greg Markby et al. · Autophagy · 2025 · 24 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Metformin protects against vascular calcification through the selective degradation of Runx2 by the p62 autophagy receptor

Kanchan Phadwal, Eve Koo, Ross A. Jones et al. · Journal of Cellular Physiology · 2022 · 19 citations · Full text

Life Sciences, Cell Biology, Pharmacology +17