Impaired Development of Th2 Cells in IL-13-Deficient Mice

Grahame J. McKenzie, Claire Emson, Sarah E. Bell, +6

Immunity

InflammationCytokineTh2 CellsAutoimmune DiseaseLymphocyte Development +5

IL-4 Induces Characteristic Th2 Responses Even in the Combined Absence of IL-5, IL-9, and IL-13

Padraic G. Fallon, Helen E. Jolin, P. H. SMITH, +5

Immunity

InflammationCombined AbsenceCytokineAutoimmune DiseaseAllergy +6

Simultaneous Disruption of Interleukin (IL)-4 and IL-13 Defines Individual Roles in T Helper Cell Type 2–mediated Responses

Grahame J. McKenzie, Padraic G. Fallon, Claire Emson, +2

The Journal of Experimental Medicine

Adaptive Immune SystemImmunologyImmune RegulationImmunologic MechanismCd4 T Cell Responses +19

Effect of tezepelumab on airway inflammatory cells, remodelling, and hyperresponsiveness in patients with moderate-to-severe uncontrolled asthma (CASCADE): a double-blind, randomised, placebo-controlled, phase 2 trial

Sarah Diver, Latifa Khalfaoui, Claire Emson, +9

The Lancet Respiratory Medicine

InflammationAsthmaAnti-inflammatoryLung InflammationImmunology +7

Efficacy and safety of benralizumab in chronic rhinosinusitis with nasal polyps: A randomized, placebo-controlled trial

Claus Bachert, Joseph K. Han, Martin Y. Desrosiers, +13

Journal of Allergy and Clinical Immunology

RheumatologyNasal PolypsAllergyAllergy MedicineImmunology +8

Pulmonary arterial remodeling induced by a Th2 immune response

Eleen Daley, Claire Emson, Christophe Guignabert, +9

The Journal of Experimental Medicine

Mfge8 diminishes the severity of tissue fibrosis in mice by binding and targeting collagen for uptake by macrophages

Kamran Atabai, Sina Jamé, Nabil Azhar, +12

Journal of Clinical Investigation

Acute Lung InjuryAccumulated CollagenInflammatory Lung DiseaseLung InflammationImmunology +19

Interleukin (IL)-4–independent Induction of Immunoglobulin (Ig)E, and Perturbation of  T Cell Development in Transgenic Mice Expressing IL-13

Claire Emson, Sarah E. Bell, Alison Jones, +2

The Journal of Experimental Medicine

Lymphocyte DevelopmentImmune RegulationImmunologyImmunologic Mechanism-4–Independent Induction +18

Intraclonal Complexity in Chronic Lymphocytic Leukemia: Fractions Enriched in Recently Born/Divided and Older/Quiescent Cells

Carlo Calissano, Rajendra N. Damle, Sonia Marsilio, +17

Molecular Medicine

Comparison of Proteomic Assessment Methods in Multiple Cohort Studies

Laura M. Raffield, Hong Dang, Katherine Pratte, +34

PROTEOMICS

AsthmaPulmonary CareInflammatory Lung DiseaseAdvanced Lung DiseaseLung Inflammation +25