Pathogenicity and immunogenicity of attenuated, nef-deleted HIV-1 strains in vivo

Paul R. Gorry, Dale A. McPhee, Erin E. Verity, +13

Retrovirology

Pembrolizumab induces HIV latency reversal in people living with HIV and cancer on antiretroviral therapy

Thomas S. Uldrick, Scott V. Adams, Rémi Fromentin, +21

Science Translational Medicine

Asn 362 in gp120 contributes to enhanced fusogenicity by CCR5-restricted HIV-1 envelope glycoprotein variants from patients with AIDS

Jasminka Sterjovski, Melissa J. Churchill, Anne Ellett, +13

Retrovirology

HIV-1 Escape from the CCR5 Antagonist Maraviroc Associated with an Altered and Less-Efficient Mechanism of gp120-CCR5 Engagement That Attenuates Macrophage Tropism

Michael Roche, Martin R. Jakobsen, Jasminka Sterjovski, +9

Journal of Virology

InflammationHiv-1 EscapeMvc ResultsMedicineAttenuates Macrophage Tropism +13

A common mechanism of clinical HIV-1 resistance to the CCR5 antagonist maraviroc despite divergent resistance levels and lack of common gp120 resistance mutations

Michael Roche, Hamid Salimi, Renee C. Duncan, +17

Retrovirology

Intact HIV Proviruses Persist in the Brain Despite Viral Suppression with ART

Catherine R. Cochrane, Thomas A. Angelovich, Sarah J. Byrnes, +16

Annals of Neurology

HIV-1 Entry and Trans-Infection of Astrocytes Involves CD81 Vesicles

Lachlan Gray, Stuart Turville, Tina L. Hitchen, +7

PLoS ONE

Viral ReplicationVirus EntryImmunologyViral PathogenesisImmunotherapy +14

i-bodies, Human Single Domain Antibodies That Antagonize Chemokine Receptor CXCR4

Katherine Griffiths, Olan Dolezal, Benjamin Cao, +20

Journal of Biological Chemistry

Molecular ImmunologyChemokine BiologyImmunologyTumor ImmunityImmunologic Mechanism +4

An altered and more efficient mechanism of CCR5 engagement contributes to macrophage tropism of CCR5-using HIV-1 envelopes

Jasminka Sterjovski, Michael Roche, Melissa J. Churchill, +10

Virology

Human RetrovirusImmunologyAntiviral ResponseCcr5 Engagement ContributesCcr5-using Hiv-1 Envelopes +8

Tissue-Specific Sequence Alterations in the Human Immunodeficiency Virus Type 1 Envelope Favoring CCR5 Usage Contribute to Persistence of Dual-Tropic Virus in the Brain

Lachlan Gray, Michael Roche, Melissa J. Churchill, +12

Journal of Virology