Fouad H. Darras

Neuroprotective Tri- and Tetracyclic BChE Inhibitors Releasing Reversible Inhibitors upon Carbamate Transfer

Fouad H. Darras, Beata Kling, Jörg Heilmann et al. · ACS Medicinal Chemistry Letters · 2012 · 95 citations · Full text

Medicine, Neuroscience, Pharmacology +17

Synthesis, Biological Evaluation, and Computational Studies of Tri- and Tetracyclic Nitrogen-Bridgehead Compounds as Potent Dual-Acting AChE Inhibitors and<i>h</i>H₃Receptor Antagonists

Fouad H. Darras, Steffen Pockes, Guozheng Huang et al. · ACS Chemical Neuroscience · 2014 · 78 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Identification of a neuroprotective and selective butyrylcholinesterase inhibitor derived from the natural alkaloid evodiamine

Guozheng Huang, Beata Kling, Fouad H. Darras et al. · European Journal of Medicinal Chemistry · 2014 · 70 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +11

Amine substitution of quinazolinones leads to selective nanomolar AChE inhibitors with ‘inverted’ binding mode

Fouad H. Darras, Sarah Wehle, Guozheng Huang et al. · Bioorganic & Medicinal Chemistry · 2014 · 56 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

The dual-acting AChE inhibitor and H3 receptor antagonist UW-MD-72 reverses amnesia induced by scopolamine or dizocilpine in passive avoidance paradigm in rats

Bassem Sadek, Nadia Khan, Fouad H. Darras et al. · Physiology & Behavior · 2016 · 41 citations

Medicine, Neuroscience, Pharmacology +14