Sarah Wehle

Acetylcholinesterase Inhibitors with Photoswitchable Inhibition of β-Amyloid Aggregation

Xinyu Chen, Sarah Wehle, Natascha Kuzmanovic et al. · ACS Chemical Neuroscience · 2014 · 111 citations · Full text

β-Amyloid Aggregation, Engineering, Photochromic Cholinesterase Inhibitors +19

Discovery of Highly Selective and Nanomolar Carbamate-Based Butyrylcholinesterase Inhibitors by Rational Investigation into Their Inhibition Mode

Edgar Sawatzky, Sarah Wehle, Beata Kling et al. · Journal of Medicinal Chemistry · 2016 · 92 citations · Full text

Combinatorial Chemistry, Drug Target, Chemical Biology +17

Synthesis, Biological Evaluation, and Computational Studies of Tri- and Tetracyclic Nitrogen-Bridgehead Compounds as Potent Dual-Acting AChE Inhibitors and<i>h</i>H₃Receptor Antagonists

Fouad H. Darras, Steffen Pockes, Guozheng Huang et al. · ACS Chemical Neuroscience · 2014 · 77 citations · Full text

Novel Tacrine‐Grafted Ugi Adducts as Multipotent Anti‐Alzheimer Drugs: A Synthetic Renewal in Tacrine–Ferulic Acid Hybrids

Mohamed Benchekroun, Manuela Bartolini, Javier Egea et al. · ChemMedChem · 2014 · 72 citations

Amine substitution of quinazolinones leads to selective nanomolar AChE inhibitors with ‘inverted’ binding mode

Fouad H. Darras, Sarah Wehle, Guozheng Huang et al. · Bioorganic & Medicinal Chemistry · 2014 · 56 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Drug Target +13