Higher-Order Inter-chromosomal Hubs Shape 3D Genome Organization in the Nucleus

Sofia A. Quinodoz, Noah Ollikainen, Barbara Tabak, +17

Cell

ChromatinPattern FormationGenome OrganizationCell DivisionChromatin Remodeling +9

SARS-CoV-2 Disrupts Splicing, Translation, and Protein Trafficking to Suppress Host Defenses

Abhik K. Banerjee, Mario R. Blanco, Emily A. Bruce, +19

Cell

Suppress Host DefensesViral ReplicationHuman RnasNeurovirologySars-cov-2 Disrupts Splicing +13

RNA promotes the formation of spatial compartments in the nucleus

Sofia A. Quinodoz, Joanna W. Jachowicz, Prashant Bhat, +10

Cell

Developmental BiologyRna BiologySpatial CompartmentsMorphogenesisGene Expression +4

CasA mediates Cas3-catalyzed target degradation during CRISPR RNA-guided interference

Megan L. Hochstrasser, David W. Taylor, Prashant Bhat, +4

Proceedings of the National Academy of Sciences

Cascade ComplexCrispr RnaNatural SciencesCrispr-associated ComplexDna Replication +9

Surveillance and Processing of Foreign DNA by the Escherichia coli CRISPR-Cas System

Sy Redding, Samuel H. Sternberg, Myles Marshall, +6

Cell

Genome organization around nuclear speckles drives mRNA splicing efficiency

Prashant Bhat, Amy Chow, Benjamin Emert, +15

Nature

Transcriptional RegulationNuclear SpecklesGeneticsRna SplicingGene Expression +3

RNA promotes the formation of spatial compartments in the nucleus

Sofia A. Quinodoz, Prashant Bhat, Noah Ollikainen, +8

Nuclear StructureGeneticsRna SplicingMolecular BiologyEpigenetics +22

Interplay Between Duration of Androgen Deprivation Therapy and External Beam Radiotherapy With or Without a Brachytherapy Boost for Optimal Treatment of High-risk Prostate Cancer

Amar U. Kishan, Alison Steigler, James W. Denham, +56

JAMA Oncology

Performance of a Prostate-Specific Membrane Antigen Positron Emission Tomography/Computed Tomography–Derived Risk-Stratification Tool for High-risk and Very High-risk Prostate Cancer

Michael Xiang, Ting Martin, Ricky R. Savjani, +61

JAMA Network Open

Simultaneous mapping of 3D structure and nascent RNAs argues against nuclear compartments that preclude transcription

Isabel N. Goronzy, Sofia A. Quinodoz, Joanna W. Jachowicz, +3

Cell Reports