James Heyes

RNAi-mediated gene silencing in non-human primates

Tracy Zimmermann, Amy C. H. Lee, Akin Akinc et al. · Nature · 2006 · 1.3K citations

Genetics, Rnai-mediated Gene, Antisense Therapy +1

Cationic lipid saturation influences intracellular delivery of encapsulated nucleic acids

James Heyes, Lorne Palmer, K. Helen Bremner et al. · Journal of Controlled Release · 2005 · 554 citations

Cell-based Drug Delivery, Biochemistry, Natural Sciences +4

Lyophilization provides long-term stability for a lipid nanoparticle-formulated, nucleoside-modified mRNA vaccine

Hiromi Muramatsu, Kieu Lam, Csaba Bajusz et al. · Molecular Therapy · 2022 · 273 citations · Full text

Stabilized plasmid–lipid particles containing PEG-diacylglycerols exhibit extended circulation lifetimes and tumor selective gene expression

Ellen Ambegia, Steven M. Ansell, P.R. Cullis et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 2005 · 201 citations

Lipid Preparation, Plasmid–lipid Particles, Cancer Cell Biology +9

Synthesis of Novel Cationic Lipids:  Effect of Structural Modification on the Efficiency of Gene Transfer

James Heyes, Dan Niculescu‐Duvaz, Robert G. Cooper et al. · Journal of Medicinal Chemistry · 2001 · 155 citations