Kieu Lam

Rational design of cationic lipids for siRNA delivery

Sean C. Semple, Akin Akinc, Jianxin Chen et al. · Nature Biotechnology · 2010 · 1.8K citations

Pharmacy, Molecular Pharmaceutics, Pharmaceutics +16

RNAi-mediated gene silencing in non-human primates

Tracy Zimmermann, Amy C. H. Lee, Akin Akinc et al. · Nature · 2006 · 1.3K citations

Life Sciences, Genetics, Molecular Biology +8

Lyophilization provides long-term stability for a lipid nanoparticle-formulated, nucleoside-modified mRNA vaccine

Hiromi Muramatsu, Kieu Lam, Csaba Bajusz et al. · Molecular Therapy · 2022 · 310 citations · Full text

Veterinary Medicine, Biotechnology, Molecular Biology +17

Added to pre-existing inflammation, mRNA-lipid nanoparticles induce inflammation exacerbation (IE)

Hamideh Parhiz, Priyal Patel, Tyler E. Papp et al. · Journal of Controlled Release · 2021 · 146 citations · Full text

Life Sciences, Immunology, Pharmaceutics +16

Optimizing Lipid Nanoparticles for Delivery in Primates

Kieu Lam, Petra Schreiner, Ada W. S. Leung et al. · Advanced Materials · 2023 · 129 citations · Full text

Pharmacy, Pharmaceutics, Pharmacology +17