Covid-19 Automated Diagnosis and Risk Assessment through Metabolomics and Machine Learning

Jeany Delafiori, Luiz Cláudio Navarro, Rinaldo Focaccia Siciliano, +27

Analytical Chemistry

Machine LearningMetabolomic ProfilingDisease DetectionCovid-19 EpidemiologyCovid-19 +18

Insulin Reverses D-Glucose–Increased Nitric Oxide and Reactive Oxygen Species Generation in Human Umbilical Vein Endothelial Cells

Marcelo González, Susana Rojas, Pía Avila, +13

PLoS ONE

Maternal Hypercholesterolemia in Pregnancy Associates With Umbilical Vein Endothelial Dysfunction

Andrea Leiva, Camila Diez de Medina, Rocío Salsoso, +7

Arteriosclerosis Thrombosis and Vascular Biology

Human umbilical vein endothelium-derived exosomes play a role in foetoplacental endothelial dysfunction in gestational diabetes mellitus

Tamara Sáez, Rocío Salsoso, Andrea Leiva, +4

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Foetoplacental Endothelial DysfunctionAngiogenesisDevelopmental BiologyNatural SciencesDiabetes +8

Insulin requires normal expression and signaling of insulin receptor A to reverse gestational diabetes‐reduced adenosine transport in human umbilical vein endothelium

Francisco Westermeier, Carlos Salomón, Marcelo Farías, +9

The FASEB Journal

Leptin Induces Oxidative Stress Through Activation of NADPH Oxidase in Renal Tubular Cells: Antioxidant Effect of L‐Carnitine

Antonio J. Blanca, María V. Ruiz‐Armenta, Sonia Zambrano, +6

Journal of Cellular Biochemistry

Nadph OxidaseLipid PeroxidationRenal InflammationRedox BiologyOxidative Stress +20

Maternal supraphysiological hypercholesterolemia associates with endothelial dysfunction of the placental microvasculature

Bárbara Fuenzalida, Bastián Sobrevia, Claudette Cantin, +6

Scientific Reports

Placental MicrovasculatureGynecologyOxidative StressHigh-risk PregnancyPublic Health +20

Cross-sectional and longitudinal lipid determination studies in pregnant women reveal an association between increased maternal LDL cholesterol concentrations and reduced human umbilical vein relaxation

Andrea Leiva, Rocío Salsoso, Tamara Sáez, +3

Placenta

Cardiovascular DiseasePhysiologyMaternal HealthPregnancyPregnant Women +6

Insulin restores l-arginine transport requiring adenosine receptors activation in umbilical vein endothelium from late-onset preeclampsia

Rocío Salsoso, Enrique Guzmán‐Gutiérrez, Tamara Sáez, +9

Placenta

Late-onset PreeclampsiaMolecular PhysiologyL-arginine TransportMedicinePhysiology +9

Maternal insulin therapy does not restore foetoplacental endothelial dysfunction in gestational diabetes mellitus

Mario Subiabre, Luis Silva, Roberto Villalobos-Labra, +7

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Foetoplacental Endothelial DysfunctionMaternal Insulin TherapyDiabetesGynecologyMaternal Health +6