HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and <i>Irx1/2</i>

Claire Heliot, Audrey Desgrange, Isabelle Buisson, +5

Development

Molecular RegulationRenal VesiclesOrgan DevelopmentCellular PhysiologyTranscriptional Regulation +20

Mutations in GREB1L Cause Bilateral Kidney Agenesis in Humans and Mice

Lara De Tomasi, Pierre David, Camille Humbert, +27

The American Journal of Human Genetics

UrologyDevelopmental BiologyMedicineGeneticsRenal Pathology +5

A predictive model of asymmetric morphogenesis from 3D reconstructions of mouse heart looping dynamics

Jean‐François Le Garrec, Jorge N. Domínguez, Audrey Desgrange, +7

eLife

HNF1B controls epithelial organization and cell polarity during ureteric bud branching and collecting duct morphogenesis

Audrey Desgrange, Claire Heliot, Ilya Skovorodkin, +6

Development

Transient Nodal Signaling in Left Precursors Coordinates Opposed Asymmetries Shaping the Heart Loop

Audrey Desgrange, Jean‐François Le Garrec, Ségolène Bernheim, +2

Developmental Cell

Cardiac MuscleCardiomyopathyTransient Nodal SignalingSignal TransductionDevelopmental Biology +10

Novel fixed Z-dimension (FiZD) kidney primordia and an organoid culture system for time-lapse confocal imaging

Ulla Saarela, Saad Ullah Akram, Audrey Desgrange, +7

Development

Pseudodynamic analysis of heart tube formation in the mouse reveals strong regional variability and early left–right asymmetry

Isaac Esteban, Patrick Schmidt, Audrey Desgrange, +5

Nature Cardiovascular Research

Standardised imaging pipeline for phenotyping mouse laterality defects and associated heart malformations, at multiple scales and multiple stages

Audrey Desgrange, Johanna Lokmer, Carmen Marchiol, +2

Disease Models & Mechanisms

Identification of Greb1l as a genetic determinant of crisscross heart in mice showing torsion of the heart tube by shortage of progenitor cells

Ségolène Bernheim, Adrien Borgel, Jean‐François Le Garrec, +12

Developmental Cell