C U Lambe

Metabolic activation of the nucleoside analog 9-[( 2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine in human diploid fibroblasts infected with human cytomegalovirus.

Karen K. Biron, Sylvia C. Stanat, J B Sorrell et al. · Proceedings of the National Academy of Sciences · 1985 · 236 citations · Full text

Metabolic Activation, Molecular Biology, Antiviral Drug +17

A human cytomegalovirus mutant resistant to the nucleoside analog 9-([2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine (BW B759U) induces reduced levels of BW B759U triphosphate.

Karen K. Biron, James A. Fyfe, Sylvia C. Stanat et al. · Proceedings of the National Academy of Sciences · 1986 · 154 citations

Bw B759u Triphosphate, Immunology, Molecular Biology +16

2-Amino-6-methoxypurine arabinoside: an agent for T-cell malignancies.

C U Lambe, D R Averett, Melanie Paff et al. · PubMed · 1995 · 96 citations

Medicinal Chemistry, Aldehyde Dehydrogenase, Cellular Enzymology +15

Inhibition by ganciclovir of cell growth and DNA synthesis of cells biochemically transformed with herpesvirus genetic information

M H St Clair, C U Lambe, P A Furman · Antimicrobial Agents and Chemotherapy · 1987 · 91 citations · Full text

Viral Replication, Molecular Virology, Synthetic Virology +12

Inhibition of cellular alpha DNA polymerase and herpes simplex virus-induced DNA polymerases by the triphosphate of BW759U

M H St Clair, Wayne H. Miller, Richard L. Miller et al. · Antimicrobial Agents and Chemotherapy · 1984 · 74 citations · Full text

Viral Replication, Molecular Virology, Natural Sciences +14