Class-Switch Recombination Occurs Infrequently in Germinal Centers

Jonathan A. Roco, Luka Mesin, Sebastian Binder, +17

Immunity

Germ CellGerminal CentersGeneticsMolecular GeneticsChromosomal Rearrangement +3

Restricted Clonality and Limited Germinal Center Reentry Characterize Memory B Cell Reactivation by Boosting

Luka Mesin, Ariën Schiepers, Jonatan Ersching, +6

Cell

Molecular fate-mapping of serum antibody responses to repeat immunization

Ariën Schiepers, Marije F. L. van ’t Wout, Allison J. Greaney, +10

Nature

Autoimmune DiseaseMolecular Fate-mappingImmunologyAntibody ScreeningAutoimmunity +4

Expression of Foxp3 by T follicular helper cells in end-stage germinal centers

Johanne T. Jacobsen, Wei Hu, Tiago B. R. Castro, +10

Science

Tunable dynamics of B cell selection in gut germinal centres

Carla R. Nowosad, Luka Mesin, Tiago B. R. Castro, +8

Nature

BiologyPattern FormationB Cell SelectionDevelopmental BiologyMorphogenesis +2

Differential Interaction of the Staphylococcal Toxins Panton–Valentine Leukocidin and γ-Hemolysin CB with Human C5a Receptors

András N. Spaan, Ariën Schiepers, Carla J. C. de Haas, +10

The Journal of Immunology

ToxinologyMicrobial PathogensInnate Immune SystemImmunologyStaphylococcus Aureus +19

Generation of Immunity against Pathogens via Single-Domain Antibody–Antigen Constructs

João N. Duarte, Juan J. Cragnolini, Lee Kim Swee, +8

The Journal of Immunology

Mosaic sarbecovirus nanoparticles elicit cross-reactive responses in pre-vaccinated animals

Alexander A. Cohen, Jennifer R. Keeffe, Ariën Schiepers, +23

Cell

VaccinationCross-protectionVaccine DevelopmentMolecular Fate MappingVaccine Target +10

The immunodominant antibody response to Zika virus NS1 protein is characterized by cross-reactivity to self

Cecília B. Cavazzoni, Vicente B. T. Bozza, Lucas Tostes, +17

The Journal of Experimental Medicine

Humoral ResponseViral PathogenesisImmunologyImmunodominanceBcr Sequencing +16

One-step generation of monoclonal B cell receptor mice capable of isotype switching and somatic hypermutation

Johanne T. Jacobsen, Luka Mesin, Styliani Markoulaki, +5

The Journal of Experimental Medicine