Class-Switch Recombination Occurs Infrequently in Germinal Centers

Jonathan A. Roco, Luka Mesin, Sebastian Binder, +17

Immunity

Germ CellGerminal CentersGeneticsMolecular GeneticsChromosomal Rearrangement +3

Germinal center B cells recognize antigen through a specialized immune synapse architecture

Carla R. Nowosad, Katelyn M. Spillane, Pavel Tolar

Nature Immunology

Autoimmune DiseaseAdaptive Immune SystemHumoral ResponseImmunologyAntigen Processing +7

Dynamic regulation of TFH selection during the germinal centre reaction

Julia Merkenschlager, Shlomo Finkin, Víctor Ramos, +10

Nature

Dynamic RegulationSignal TransductionDevelopmental BiologyGerm CellMorphogenesis +4

Tunable dynamics of B cell selection in gut germinal centres

Carla R. Nowosad, Luka Mesin, Tiago B. R. Castro, +8

Nature

BiologyPattern FormationB Cell SelectionDevelopmental BiologyMorphogenesis +2

WASp-dependent actin cytoskeleton stability at the dendritic cell immunological synapse is required for extensive, functional T cell contacts

Dessislava Malinova, Marco Fritzsche, Carla R. Nowosad, +7

Journal of Leukocyte Biology

Clonal replacement sustains long-lived germinal centers primed by respiratory viruses

Robson Amparo de Carvalho, Jonatan Ersching, Alexandru Barbulescu, +15

Cell

Viral ReplicationViral EvolutionMolecular VirologyEvolutionary BiologyPathogenesis +5

The rapid generation of recombinant functional monoclonal antibodies from individual, antigen-specific bone marrow-derived plasma cells isolated using a novel fluorescence-based method

Alison Clargo, Ashley R Hudson, Welcome Ndlovu, +16

mAbs

Immunocytochemical TechniqueEngineeringImmunologyBlood CellImmunophenotyping +17

Myosin IIa Promotes Antibody Responses by Regulating B Cell Activation, Acquisition of Antigen, and Proliferation

Robbert Hoogeboom, Elizabeth Natkanski, Carla R. Nowosad, +4

Cell Reports

Quorum-sensing agr system of Staphylococcus aureus primes gene expression for protection from lethal oxidative stress

Magdalena Podkowik, Andrew I. Perault, Gregory Putzel, +23

eLife

MHC class II cell-autonomously regulates self-renewal and differentiation of normal and malignant B cells

Julia Merkenschlager, Urszula Eksmond, Luca Danelli, +5

Blood