Adel Chergui

Synthesis and Biological Evaluation of the First Dual Tyrosyl-DNA Phosphodiesterase I (Tdp1)–Topoisomerase I (Top1) Inhibitors

Trung Xuan Nguyen, Andrew Morrell, Martin Conda‐Sheridan et al. · Journal of Medicinal Chemistry · 2012 · 87 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Synthesis and Biological Evaluation of New Carbohydrate-Substituted Indenoisoquinoline Topoisomerase I Inhibitors and Improved Syntheses of the Experimental Anticancer Agents Indotecan (LMP400) and Indimitecan (LMP776)

Daniel E. Beck, Keli Agama, Christophe Marchand et al. · Journal of Medicinal Chemistry · 2014 · 70 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Synthesis and Biological Evaluation of Indenoisoquinolines That Inhibit Both Tyrosyl-DNA Phosphodiesterase I (Tdp1) and Topoisomerase I (Top1)

Martin Conda‐Sheridan, P. Venkat Reddy, Andrew Morrell et al. · Journal of Medicinal Chemistry · 2012 · 69 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

5-Arylidenethioxothiazolidinones as Inhibitors of Tyrosyl–DNA Phosphodiesterase I

Venkata Ramana Sirivolu, Sanjeev Kumar V. Vernekar, Christophe Marchand et al. · Journal of Medicinal Chemistry · 2012 · 63 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Discovery and Structure–Activity Relationship of Novel 2,3-Dihydrobenzofuran-7-carboxamide and 2,3-Dihydrobenzofuran-3(2<i>H</i>)-one-7-carboxamide Derivatives as Poly(ADP-ribose)polymerase-1 Inhibitors

Maulik Patel, Aaditya Bhatt, Jamin D. Steffen et al. · Journal of Medicinal Chemistry · 2014 · 52 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17