Claudio Isella

A Molecularly Annotated Platform of Patient-Derived Xenografts (“Xenopatients”) Identifies HER2 as an Effective Therapeutic Target in Cetuximab-Resistant Colorectal Cancer

Andrea Bertotti, Giorgia Migliardi, Francesco Galimi et al. · Cancer Discovery · 2011 · 938 citations · Full text

Stromal contribution to the colorectal cancer transcriptome

Claudio Isella, Andrea Terrasi, Sara E. Bellomo et al. · Nature Genetics · 2015 · 645 citations · Full text

Pathology, Colorectal Cancer, Colorectal Cancer Transcriptome +6

Selective analysis of cancer-cell intrinsic transcriptional traits defines novel clinically relevant subtypes of colorectal cancer

Claudio Isella, Francesco Brundu, Sara E. Bellomo et al. · Nature Communications · 2017 · 316 citations · Full text

The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets

Enzo Médico, Mariangela Russo, Gabriele Picco et al. · Nature Communications · 2015 · 299 citations · Full text

Increased Lactate Secretion by Cancer Cells Sustains Non-cell-autonomous Adaptive Resistance to MET and EGFR Targeted Therapies

Maria Apicella, Elisa Giannoni, Stephany Fiore et al. · Cell Metabolism · 2018 · 271 citations · Full text

Medicine, Egfr Targeted Therapies, Lactate Secretion +10