Rab27a and Rab27b control different steps of the exosome secretion pathway

Matías Ostrowski, Nuno Carmo, Sophie Krumeich, +17

Nature Cell Biology

Protein SecretionSignal TransductionSecretory PathwaysMedicineNatural Sciences +13

Analysis of ESCRT functions in exosome biogenesis, composition and secretion highlights the heterogeneity of extracellular vesicles

Marina Colombo, Catarina Moita, Guillaume van Niel, +7

Journal of Cell Science

Protein interaction mapping: A<i>Drosophila</i>case study

Étienne Formstecher, Sandra Aresta, Vincent Collura, +39

Genome Research

Mapping the human DC lineage through the integration of high-dimensional techniques

Peter See, Charles‐Antoine Dutertre, Jinmiao Chen, +33

Science

Tissue-resident macrophages provide a pro-tumorigenic niche to early NSCLC cells

María Casanova-Acebes, Erica Dalla, Andrew M. Leader, +24

Nature

InflammationMedicineImmunologyTumor ImmunityPathology +8

Human Macrophages Accumulate HIV‐1 Particles in MHC II Compartments

Graça Raposo, Marilyn Moore, Donald Innes, +4

Traffic

Class Ii MoleculesClass IiViral ReplicationVirus ParticlesHuman Retrovirus +13

HIV-1 Nef impairs MHC class II antigen presentation and surface expression

Pamela Stumptner-Cuvelette, Stéphanie Morchoisne, Marc Dugast, +4

Proceedings of the National Academy of Sciences

Autoimmune DiseaseMedicineHuman RetrovirusImmunologyAntiviral Response +11

Cleavage of Toll-like receptor 3 by cathepsins B and H is essential for signaling

Alejandra Garcia-Cattaneo, François-Xavier Gobert, Mélanie Müller, +5

Proceedings of the National Academy of Sciences

Innate Immune SystemImmunologyCell DeathImmunologic MechanismInnate Immunity +22

Down-Modulation of Mature Major Histocompatibility Complex Class II and Up-Regulation of Invariant Chain Cell Surface Expression Are Well-Conserved Functions of Human and Simian Immunodeficiency Virus <i>nef</i> Alleles

Michael Schindler, Stephanie Würfl, Philippe Benaroch, +6

Journal of Virology

ImmunodeficienciesImmunologyMature Mhc-iiImmunodominanceAntigen Processing +19

How MHC class II molecules reach the endocytic pathway.

Philippe Benaroch, Mamadi Yilla, Graça Raposo, +4

The EMBO Journal

Mhc Class IiSignal TransductionNatural SciencesCell TraffickingEndocytic Pathway +7