Jesper Nylandsted

Heat Shock Protein 70 Promotes Cell Survival by Inhibiting Lysosomal Membrane Permeabilization

Jesper Nylandsted, Mads Gyrd‐Hansen, Agnieszka Danielewicz et al. · The Journal of Experimental Medicine · 2004 · 543 citations · Full text

Apoptosis, Immunology, Cell Death +18

Hsp70 stabilizes lysosomes and reverts Niemann–Pick disease-associated lysosomal pathology

Thomas Kirkegaard, Anke G. Roth, Nikolaj H.T. Petersen et al. · Nature · 2010 · 513 citations · Full text

Protein Function, Lysosomal Storage Disease, Autophagy +4

Members of the heat-shock protein 70 family promote cancer cell growth by distinct mechanisms

Mikkel Rohde, Mads Daugaard, Mette Hartvig Jensen et al. · Genes & Development · 2005 · 414 citations · Full text

Distinct Mechanisms, Molecular Biology, Cancer Biology +17

Selective depletion of heat shock protein 70 (Hsp70) activates a tumor-specific death program that is independent of caspases and bypasses Bcl-2

Jesper Nylandsted, Mikkel Rohde, Karsten Brand et al. · Proceedings of the National Academy of Sciences · 2000 · 389 citations · Full text

Transformation-Associated Changes in Sphingolipid Metabolism Sensitize Cells to Lysosomal Cell Death Induced by Inhibitors of Acid Sphingomyelinase

Nikolaj H.T. Petersen, Ole Dines Olsen, Line Groth‐Pedersen et al. · Cancer Cell · 2013 · 330 citations · Full text

Mitophagy, Signal Transduction, Biochemistry +11