Evaluation of DNA Methylation Episignatures for Diagnosis and Phenotype Correlations in 42 Mendelian Neurodevelopmental Disorders

Erfan Aref‐Eshghi, Jennifer Kerkhof, Victor P. Pedro, +65

The American Journal of Human Genetics

Neurodevelopmental DisordersMendelian DisorderEpigenetic ChangeGeneticsDna Methylation +9

Nuclear localization and histone acetylation: a pathway for chromatin opening and transcriptional activation of the human β-globin locus

Dirk Schübeler, Claire Francastel, Daniel Cimbora, +3

Genes & Development

Histone ModificationsEpigenetic ChangeGeneticsEpigeneticsGene Activation +20

A Functional Enhancer Suppresses Silencing of a Transgene and Prevents Its Localization Close to Centromeric Heterochromatin

Claire Francastel, Mark C. Walters, Mark Groudine, +1

Cell

ChromatinTranscriptional RegulationLocalization CloseCentromeric HeterochromatinChromatin Structure +11

Accumulation of small murine minor satellite transcripts leads to impaired centromeric architecture and function

Haniaa Bouzinba-Ségard, Adeline Guais, Claire Francastel

Proceedings of the National Academy of Sciences

Epigenetic ChangeGeneticsEpigeneticsCellular PhysiologyTranscriptional Regulation +21

Dynamic changes in transcription factor complexes during erythroid differentiation revealed by quantitative proteomics

Marjorie Brand, Jeffrey A. Ranish, Nicolas T Kummer, +7

Nature Structural & Molecular Biology

Proteomic TechnologyDynamic ChangesSystems BiologyMedicineNatural Sciences +8

Mutations in CDCA7 and HELLS cause immunodeficiency–centromeric instability–facial anomalies syndrome

Peter Thijssen, Yuya Ito, Giacomo Grillo, +26

Nature Communications

Non-coding murine centromeric transcripts associate with and potentiate Aurora B kinase

Federica Ferri, Haniaa Bouzinba-Ségard, Guillaume Velasco, +2

Nucleic Acids Research

GeneticsCell CycleEpigeneticsCellular PhysiologySignaling Pathway +19

Steroid receptor RNA activator protein binds to and counteracts SRA RNA-mediated activation of MyoD and muscle differentiation

Florent Hubé, Guillaume Velasco, Jérôme Rollin, +2

Nucleic Acids Research

Muscle FunctionEngineeringSra NcrnaCellular PhysiologyMyod Activity +15

Nuclear relocation of a transactivator subunit precedes target gene activation

Claire Francastel, Wendy Magis, Mark Groudine

Proceedings of the National Academy of Sciences

GeneticsCell CycleGene TranscriptionGene ActivationTranscriptional Regulation +14

Dnmt3b recruitment through E2F6 transcriptional repressor mediates germ-line gene silencing in murine somatic tissues

Guillaume Velasco, Florent Hubé, Jérôme Rollin, +6

Proceedings of the National Academy of Sciences

Histone ModificationsEpigenetic ChangeGeneticsDna MethylationGerm-line Gene +23